orf1ab

Replicase polyprotein 1ab

Función

Biological Process

Molecular Function/s

Localización Celular

Keywords Uniprot

DBIdentificador
InterPro IPR009003
EMBL AY463059
EMBL AP006561
EMBL AY274119
BioGRID 4383946
Proteomes UP000137377
Pfam PF05409
EMBL AP006559
Gene3D 3.40.220.20
EMBL AY291315
BioGRID 4383938
BRENDA 3.6.4.12
InterPro IPR043472
PRIDE P0C6X7
SUPFAM SSF143076
DrugBank DB07743
SABIO-RK P0C6X7
UnipAcc Q80E51
EMBL AY322205
BRENDA 2.7.7.48
Gene3D 3.40.50.11580
InterPro IPR043504
DrugBank DB07293
EMBL AP006560
Pfam PF08717
PROSITE PS51653
SMART SM00506
Pfam PF11633
EMBL AY269391
EMBL AY291451
InterPro IPR007094
InterPro IPR036333
EMBL AY304488
UnipAcc Q808C0
Gene3D 2.40.10.10
BioGRID 4383947
ComplexPortal CPX-5711
Proteomes UP000000354
BioGRID 4383945
Pfam PF06460
SUPFAM SSF50494
Proteomes UP000153467
InterPro IPR013016
BioGRID 4383940
InterPro IPR043177
InterPro IPR021590
Proteomes UP000116947
Gene3D 3.40.220.10
EMBL AY348314
UnipAcc P59641
InterPro IPR042515
EMBL AY304486
EMBL AY283794
Gene3D 1.10.1840.10
EMBL AY278741
InterPro IPR027352
Pfam PF16348
InterPro IPR029063
Pfam PF12124
EMBL AY283798
EMBL AY278490
InterPro IPR009469
ComplexPortal CPX-5717
InterPro IPR009466
Proteomes UP000145651
Proteomes UP000121636
UnipGene rep
BioGRID 4383948
InterPro IPR038083
InterPro IPR038166
Gene3D 2.30.30.590
CDD cd18808
BioGRID 4383949
Pfam PF09401
BioGRID 4383953
UnipAcc Q80BV7
Gene3D 1.10.8.1190
DrugCentral P0C6X7
Proteomes UP000146181
SUPFAM SSF52949
Proteomes UP000172416
IntAct P0C6X7
UnipAcc Q80BV8
UnipAcc Q6WGN0
Proteomes UP000103670
EMBL AP006557
InterPro IPR024375
InterPro IPR027351
Proteomes UP000164441
UnipAcc R1AB_SARS
InterPro IPR032505
EMBL AY322207
EMBL AY282752
Pfam PF01661
BRENDA 3.4.22.B14
SUPFAM SSF140367
BioGRID 4383951
Gene3D 2.20.25.360
BioGRID 4383943
UnipAcc Q7T697
InterPro IPR036499
BioGRID 4383944
Pfam PF06471
ComplexPortal CPX-5709
InterPro IPR018995
Gene3D 1.10.150.420
EMBL AY321118
EMBL AY338174
InterPro IPR014822
InterPro IPR037204
PROSITE PS51442
InterPro IPR032592
Proteomes UP000131569
InterPro IPR014829
Proteomes UP000138690
EMBL AY427439
ChEMBL CHEMBL5118
InterPro IPR043503
SUPFAM SSF52540
BioGRID 4383942
EMBL AY286320
Gene3D 3.10.20.350
Pfam PF06478
ComplexPortal CPX-5706
BioGRID 4383950
UnipAcc P0C6X7
InterPro IPR014828
DrugBank DB08656
InterPro IPR024358
Gene3D 1.10.8.370
BioGRID 4383939
Pfam PF16251
Proteomes UP000148194
SUPFAM SSF53335
SUPFAM SSF142877
InterPro IPR043174
DrugBank DB08748
InterPro IPR037227
InterPro IPR038400
EMBL AY278489
PROSITE PS51124
ComplexPortal CPX-5719
InterPro IPR041679
BioGRID 4383941
Gene3D 3.40.220.30
EMBL AY322206
DrugBank DB08732
EMBL AY310120
EvolutionaryTrace P0C6X7
InterPro IPR037230
SUPFAM SSF160099
InterPro IPR043178
InterPro IPR022733
Gene3D 3.40.50.11020
Proteomes UP000160648
DrugBank DB14761
InterPro IPR009461
InterPro IPR043478
EMBL AY323977
Gene3D 2.40.10.250
Pfam PF11501
EMBL AY278491
InterPro IPR043502
InterPro IPR002589
SUPFAM SSF159936
SUPFAM SSF144246
Pfam PF08716
SUPFAM SSF101816
SUPFAM SSF56672
EMBL AY278554
InterPro IPR027417
InterPro IPR038123
DrugBank DB07620
EMBL AY278488
Proteomes UP000146108
PROSITE PS50507
InterPro IPR043477
ComplexPortal CPX-5707
EMBL AY283797
Proteomes UP000131955
InterPro IPR038030
ComplexPortal CPX-5710
EMBL AY304495
PROSITE PS51657
Pfam PF12379
Proteomes UP000146296
Pfam PF08710
BioGRID 4383952
Proteomes UP000109640
MINT P0C6X7
EMBL AP006558
InterPro IPR008740
Pfam PF08715
Gene3D 3.10.20.540
PROSITE PS51154
EMBL AY283795
Gene3D 3.90.70.90
InterPro IPR042570
Proteomes UP000143093
Gene3D 2.40.10.290
SMR P0C6X7
ComplexPortal CPX-5721
EMBL AY279354
EMBL AY338175
EMBL AY268049
EMBL AY283796
BindingDB P0C6X7

Estructura/s

TipoCodNombreDrogabilidad
PDB 2bx4 HYDROLASE 0.685
PDB 1z1j HYDROLASE 0.74
PDB 2vj1 HYDROLASE 0.577
PDB 4tww HYDROLASE/HYDROLASE INHIBITOR 0.584
PDB 4twy HYDROLASE/HYDROLASE INHIBITOR 0.738
PDB 2bx3 HYDROLASE 0.8
PDB 3e9s HYDROLASE 0.58
PDB 5n5o HYDROLASE 0.647
PDB 5e6j HYDROLASE 0.437
PDB 2d2d HYDROLASE 0.698
PDB 2gx4 HYDROLASE 0.763
PDB 2h85 VIRAL PROTEIN 0.693
PDB 1q2w HYDROLASE 0.499
PDB 4zuh HYDROLASE/PEPTIDE 0.475
PDB 2gt7 HYDROLASE 0.426
PDB 2z3e HYDROLASE/HYDROLASE INHIBITOR 0.664
PDB 2fav VIRAL PROTEIN 0.91
PDB 2z9l HYDROLASE 0.599
PDB 2ga6 VIRAL PROTEIN 0.449
PDB 2z94 HYDROLASE 0.499
PDB 2jzf VIRAL PROTEIN 0.863
PDB 2acf VIRAL PROTEIN 0.855
PDB 2jze VIRAL PROTEIN 0.924
PDB 6nus VIRAL PROTEIN
PDB 2alv HYDROLASE 0.63
PDB 2gz8 HYDROLASE 0.683
PDB 1qz8 UNKNOWN FUNCTION 0.823
PDB 2fe8 HYDROLASE 0.518
PDB 2qiq VIRAL PROTEIN 0.684
PDB 2hsx VIRAL PROTEIN, HYDROLASE 0.764
PDB 5nfy TRANSFERASE 0.722
PDB 2gt8 HYDROLASE 0.771
PDB 2q6g HYDROLASE 0.507
PDB 2amq HYDROLASE 0.656
PDB 3ebn HYDROLASE 0.717
PDB 2h2z VIRAL PROTEIN 0.544
PDB 1wof HYDROLASE 0.723
PDB 1ysy VIRAL PROTEIN 0.799
PDB 2z3c HYDROLASE/HYDROLASE INHIBITOR 0.61
PDB 2hob VIRAL PROTEIN 0.67
PDB 6nur VIRAL PROTEIN
PDB 2g9t VIRAL PROTEIN 0.656
PDB 2gri VIRAL PROTEIN 0.889
PDB 2amd HYDROLASE 0.681
PDB 2z9g HYDROLASE 0.74
PDB 2c3s HYDROLASE 0.66
PDB 2a5k HYDROLASE 0.6
PDB 5c5o HYDROLASE/HYDROLASE INHIBITOR 0.539
PDB 2z3d HYDROLASE/HYDROLASE INHIBITOR 0.527
PDB 2a5i HYDROLASE 0.583
PDB 1uk3 HYDROLASE 0.662
PDB 5f22 HYDROLASE 0.531
PDB 2k87 viral protein, RNA binding protein 0.473
PDB 2rnk VIRAL PROTEIN 0.863
PDB 2jzd VIRAL PROTEIN 0.916
PDB 2pwx HYDROLASE 0.928
PDB 3r24 Transferase, Viral Protein 0.38
PDB 2z9k HYDROLASE 0.664
PDB 2gz9 HYDROLASE 0.713
PDB 2fyg VIRAL PROTEIN 0.447
PDB 2a5a HYDROLASE 0.674
PDB 5c8u TRANSFERASE 0.866
PDB 2gdt VIRAL PROTEIN, HYDROLASE 0.764
PDB 1z1i HYDROLASE 0.615
PDB 2ahm Viral protein, Replication 0.537
PDB 2z9j HYDROLASE 0.776
PDB 2gtb HYDROLASE 0.797
PDB 2xyv TRANSFERASE/VIRAL PROTEIN 0.621
PDB 6jyt HYDROLASE 0.654
PDB 1uj1 HYDROLASE 0.561
PDB 3d62 HYDROLASE 0.546
PDB 2v6n VIRAL PROTEIN 0.706
PDB 2gz7 HYDROLASE 0.44
PDB 1uk2 HYDROLASE 0.33
PDB 2xyr TRANSFERASE/VIRAL PROTEIN 0.48
PDB 1uw7 VIRAL PROTEIN
PDB 5c8s TRANSFERASE 0.755
PDB 2qc2 HYDROLASE 0.67
PDB 4wy3 HYDROLASE/HYDROLASE INHIBITOR 0.503
PDB 2xyq TRANSFERASE/VIRAL PROTEIN 0.584
PDB 2qcy HYDROLASE 0.288
PDB 5c8t TRANSFERASE 0.685
PDB 2ozk VIRAL PROTEIN 0.731
PDB 2duc HYDROLASE 0.384
PDB 2op9 HYDROLASE 0.717
PDB 2idy VIRAL PROTEIN 0.889
PDB 5n19 HYDROLASE 0.621
PDB 5c5n HYDROLASE/HYDROLASE INHIBITOR 0.587
PDB 5b6o HYDROLASE 0.301
PDB 2rhb VIRAL PROTEIN 0.698
PDB 1uk4 HYDROLASE 0.653

Anotación

Tipo Identificador InicioFin
chain Host translation inhibitor nsp1 (PRO_0000037309) 1 180
chain Non-structural protein 2 (PRO_0000037310) 181 818
chain Non-structural protein 3 (PRO_0000037311) 819 2740
chain Non-structural protein 4 (PRO_0000283841) 2741 3240
chain 3C-like proteinase (PRO_0000037312) 3241 3546
chain Non-structural protein 6 (PRO_0000037313) 3547 3836
chain Non-structural protein 7 (PRO_0000037314) 3837 3919
chain Non-structural protein 8 (PRO_0000037315) 3920 4117
chain Non-structural protein 9 (PRO_0000037316) 4118 4230
chain Non-structural protein 10 (PRO_0000037317) 4231 4369
chain RNA-directed RNA polymerase (PRO_0000037318) 4370 5301
chain Helicase (PRO_0000037319) 5302 5902
chain Proofreading exoribonuclease (PRO_0000037320) 5903 6429
chain Uridylate-specific endoribonuclease (PRO_0000037321) 6430 6775
chain 2'-O-methyltransferase (PRO_0000037322) 6776 7073
topological domain Cytoplasmic 1 2202
transmembrane region Helical 2203 2223
topological domain Lumenal 2224 2303
transmembrane region Helical 2304 2324
topological domain Cytoplasmic 2325 2350
transmembrane region Helical 2351 2371
topological domain Lumenal 2372 2754
transmembrane region Helical 2755 2775
topological domain Cytoplasmic 2776 2991
transmembrane region Helical 2992 3012
topological domain Lumenal 3013 3021
transmembrane region Helical 3022 3042
topological domain Cytoplasmic 3043 3053
transmembrane region Helical 3054 3074
topological domain Lumenal 3075 3076
transmembrane region Helical 3077 3097
topological domain Cytoplasmic 3098 3104
transmembrane region Helical 3105 3125
topological domain Lumenal 3126 3141
transmembrane region Helical 3142 3162
topological domain Cytoplasmic 3163 3563
transmembrane region Helical 3564 3584
topological domain Lumenal 3585 3585
transmembrane region Helical 3586 3606
topological domain Cytoplasmic 3607 3611
transmembrane region Helical 3612 3632
topological domain Lumenal 3633 3657
transmembrane region Helical 3658 3678
topological domain Cytoplasmic 3679 3684
transmembrane region Helical 3685 3704
topological domain Lumenal 3705 3727
transmembrane region Helical 3728 3748
topological domain Cytoplasmic 3749 3755
transmembrane region Helical 3756 3776
topological domain Lumenal 3777 7073
Other domain of interest Macro 1003 1169
Other domain of interest Peptidase C16 1611 1875
Other domain of interest Peptidase C30 3241 3546
Other domain of interest RdRp catalytic 4981 5143
Other domain of interest CV ZBD 5302 5385
Other domain of interest (+)RNA virus helicase ATP-binding 5558 5739
Other domain of interest (+)RNA virus helicase C-terminal 5740 5909
zinc finger region C4-type 1729 1766
zinc finger region zinc finger region 4304 4320
zinc finger region zinc finger region 4347 4360
Nucleotide-binding region ATP 5583 5590
region of interest HD1 2092 2371
region of interest HD2 2755 3162
region of interest HD3 3564 3776
compositionally biased region Glu-rich 930 1001
compositionally biased region Poly-Leu 2210 2213
compositionally biased region Poly-Cys 3766 3769
active site For PL-PRO activity 1651 1651
active site For PL-PRO activity 1812 1812
active site For 3CL-PRO activity 3281 3281
active site For 3CL-PRO activity 3385 3385
metal ion-binding site Zinc 4304 4304
metal ion-binding site Zinc 4307 4307
metal ion-binding site Zinc 4313 4313
metal ion-binding site Zinc 4320 4320
metal ion-binding site Zinc 4347 4347
metal ion-binding site Zinc 4350 4350
metal ion-binding site Zinc 4358 4358
metal ion-binding site Zinc 1 5306 5306
metal ion-binding site Zinc 1 5309 5309
metal ion-binding site Zinc 2 5317 5317
metal ion-binding site Zinc 1 5320 5320
metal ion-binding site Zinc 1 5327 5327
metal ion-binding site Zinc 2 5330 5330
metal ion-binding site Zinc 2 5334 5334
metal ion-binding site Zinc 2 5340 5340
metal ion-binding site Zinc 3 5351 5351
metal ion-binding site Zinc 3 5356 5356
metal ion-binding site Zinc 3 5373 5373
metal ion-binding site Zinc 3 5376 5376
Other site of interest Cleavage 180 181
Other site of interest Cleavage; by PL-PRO 818 819
Other site of interest Cleavage; by PL-PRO 2740 2741
Other site of interest Cleavage; by 3CL-PRO 3240 3241
Other site of interest Cleavage; by 3CL-PRO 3546 3547
Other site of interest Cleavage; by 3CL-PRO 3836 3837
Other site of interest Cleavage; by 3CL-PRO 3919 3920
Other site of interest Cleavage; by 3CL-PRO 4117 4118
Other site of interest Cleavage; by 3CL-PRO 4230 4231
Other site of interest Cleavage; by 3CL-PRO 4369 4370
Other site of interest Cleavage; by 3CL-PRO 5301 5302
Other site of interest Cleavage; by 3CL-PRO 5902 5903
Other site of interest Cleavage; by 3CL-PRO 6429 6430
Other site of interest Cleavage; by 3CL-PRO 6775 6776
Sequence variation in strain: Isolate GD01 () 82 82
Sequence variation in strain: Isolate GD01 () 130 130
Sequence variation in strain: Isolate SZ16 () 138 138
Sequence variation in strain: Isolate Shanghai LY () 181 181
Sequence variation in strain: Isolate GD01 () 225 225
Sequence variation in strain: Isolate Shanghai LY () 249 249
Sequence variation in strain: Isolate BJ04 () 306 306
Sequence variation in strain: Isolate SZ3 () 549 549
Sequence variation in strain: Isolate FRA and Isolate Frankfurt-1 () 765 765
Sequence variation in strain: Isolate SZ16 () 852 852
Sequence variation in strain: Isolate BJ03 () 1004 1004
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1021 1021
Sequence variation in strain: Isolate Shanghai QXC1 () 1023 1023
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 1121 1121
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1136 1136
Sequence variation in strain: Isolate Shanghai QXC1 () 1257 1257
Sequence variation in strain: Isolate GD01 () 1319 1319
Sequence variation in strain: Isolate GD01 () 1329 1329
Sequence variation in strain: Isolate Shanghai QXC1 () 1361 1361
Sequence variation in strain: Isolate Shanghai QXC1 () 1385 1385
Sequence variation in strain: Isolate GD01 () 1538 1538
Sequence variation in strain: Isolate BJ02 () 1563 1563
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1663 1663
Sequence variation in strain: Isolate BJ03 () 1762 1762
Sequence variation in strain: Isolate BJ03 () 1776 1777
Sequence variation in strain: Isolate Shanghai QXC1 () 1790 1790
Sequence variation in strain: Isolate BJ02 () 1806 1806
Sequence variation in strain: Isolate BJ04 () 1962 1962
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 2116 2116
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 2222 2222
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 2269 2269
Sequence variation in strain: Isolate Shanghai QXC1 () 2326 2326
Sequence variation in strain: Isolate Shanghai QXC1 () 2392 2394
Sequence variation in strain: Isolate Shanghai QXC1 () 2480 2480
Sequence variation in strain: Isolate Urbani and Isolate Taiwan TC2 () 2552 2552
Sequence variation in strain: Isolate HKU-39849 () 2556 2556
Sequence variation in strain: Isolate GD01 () 2564 2564
Sequence variation in strain: Isolate Shanghai QXC1 () 2648 2648
Sequence variation in strain: Isolate HKU-39849 () 2708 2708
Sequence variation in strain: Isolate HKU-39849 () 2718 2718
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 2746 2746
Sequence variation in strain: Isolate BJ01 and Isolate BJ02 () 2770 2770
Sequence variation in strain: Isolate SIN2500, Isolate GD01 and Isolate GZ50 () 2944 2944
Sequence variation in strain: Isolate GD01 and Isolate SZ16 () 2971 2971
Sequence variation in strain: Isolate Shanghai QXC1 () 3020 3020
Sequence variation in strain: Isolate CUHK-W1, Isolate GD01, Isolate SZ3, Isolate S () 3047 3047
Sequence variation in strain: Isolate CUHK-W1, Isolate SZ3, Isolate SZ16 and Isolat () 3072 3072
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate BJ0 () 3197 3197
Sequence variation in strain: Isolate BJ02 () 3429 3429
Sequence variation in strain: Isolate BJ04 () 3488 3488
Sequence variation in strain: Isolate Shanghai QXC1 () 3717 3717
Sequence variation in strain: Isolate BJ04 () 3818 3818
Sequence variation in strain: Isolate BJ03 () 3903 3903
Sequence variation in strain: Isolate BJ02 () 3904 3904
Sequence variation in strain: Isolate Shanghai QXC1 () 3911 3911
Sequence variation in strain: Isolate Shanghai LY () 4001 4001
Sequence variation in strain: Isolate Shanghai LY () 4003 4003
Sequence variation in strain: Isolate ZJ01 () 4085 4085
Sequence variation in strain: Isolate Shanghai QXC1 () 4114 4114
Sequence variation in strain: Isolate Shanghai QXC1 () 4202 4202
Sequence variation in strain: Isolate ZJ01 () 4240 4240
Sequence variation in strain: Isolate Shanghai QXC1 () 4296 4296
Sequence variation in strain: Isolate Shanghai QXC1 () 4377 4378
Sequence variation in strain: Isolate HKU-39849 () 4411 4411
Sequence variation in strain: Isolate Shanghai QXC1 () 4459 4459
Sequence variation in strain: Isolate ZJ01 () 4592 4592
Sequence variation in strain: Isolate ZJ01 () 4910 4910
Sequence variation in strain: Isolate SZ3 () 5112 5112
Sequence variation in strain: Isolate Taiwan () 5131 5131
Sequence variation in strain: Isolate Taiwan () 5134 5135
Sequence variation in strain: Isolate GD01 () 5623 5623
Sequence variation in strain: Isolate GZ50 and Isolate SIN2500 () 5720 5720
Sequence variation in strain: Isolate ZJ01 () 5744 5744
Sequence variation in strain: Isolate CUHK-W1, Isolate BJ01, Isolate BJ02, Isolate () 5767 5767
Sequence variation in strain: Isolate FRA, Isolate Frankfurt-1 Isolate SIN2677, Iso () 6274 6274
Sequence variation in strain: Isolate Shanghai QXC1 () 6474 6474
Sequence variation in strain: Isolate BJ03 () 6700 6700
Sequence variation in strain: Isolate Shanghai QXC1 () 6721 6721
Sequence variation in strain: Isolate GD01 () 6729 6729
Sequence variation in strain: Isolate BJ02 () 6840 6840
Sequence variation in strain: Isolate BJ04 () 6862 6862
Sequence variation in strain: Isolate GD01 () 6877 6877
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 6910 6910
Sequence variation in strain: Isolate BJ03 () 6937 6937
Sequence variation in strain: Isolate BJ04 () 6992 6992
Sequence variation in strain: Isolate GD01 () 7008 7008
Sequence variation in strain: Isolate BJ04 () 7024 7024
mutagenesis site Complete loss of nsp9 dimerization. 4217 4217
mutagenesis site Complete loss of nsp9 dimerization. 4221 4221
strand strand 14 20
turn turn 23 25
helix helix 35 48
strand strand 51 54
helix helix 61 63
strand strand 68 72
strand strand 87 93
turn turn 95 98
strand strand 99 102
strand strand 105 109
strand strand 116 123
strand strand 827 829
turn turn 831 833
strand strand 839 841
strand strand 848 851
turn turn 852 856
strand strand 860 862
turn turn 869 871
helix helix 872 882
helix helix 888 894
helix helix 898 901
strand strand 907 909
strand strand 911 915
strand strand 918 920
strand strand 922 926
strand strand 1013 1021
helix helix 1023 1030
strand strand 1033 1038
helix helix 1048 1056
turn turn 1057 1059
helix helix 1060 1072
strand strand 1080 1084
turn turn 1086 1088
strand strand 1090 1095
helix helix 1100 1102
helix helix 1108 1114
helix helix 1115 1118
strand strand 1119 1124
helix helix 1130 1132
helix helix 1136 1146
strand strand 1149 1156
helix helix 1158 1168
strand strand 1345 1347
helix helix 1351 1361
strand strand 1364 1368
helix helix 1372 1381
strand strand 1389 1401
helix helix 1407 1417
strand strand 1421 1424
strand strand 1426 1428
helix helix 1429 1431
helix helix 1435 1442
strand strand 1449 1452
helix helix 1457 1467
strand strand 1544 1555
strand strand 1557 1562
helix helix 1567 1571
strand strand 1572 1576
strand strand 1582 1584
helix helix 1588 1590
strand strand 1594 1597
helix helix 1602 1612
helix helix 1619 1630
strand strand 1639 1642
turn turn 1648 1650
helix helix 1651 1661
strand strand 1667 1669
helix helix 1670 1680
helix helix 1685 1694
helix helix 1705 1713
strand strand 1722 1728
strand strand 1730 1732
strand strand 1734 1740
helix helix 1742 1745
strand strand 1746 1749
helix helix 1753 1758
strand strand 1760 1763
strand strand 1765 1785
strand strand 1790 1793
helix helix 1795 1797
strand strand 1799 1807
strand strand 1810 1826
strand strand 1829 1834
strand strand 1836 1846
strand strand 1904 1911
helix helix 1912 1921
strand strand 1929 1936
strand strand 1942 1948
helix helix 1949 1951
helix helix 1954 1956
strand strand 1963 1966
strand strand 1969 1971
helix helix 1977 1990
helix helix 3251 3254
strand strand 3257 3262
strand strand 3265 3272
strand strand 3275 3279
helix helix 3280 3283
helix helix 3286 3290
helix helix 3294 3299
helix helix 3303 3305
strand strand 3307 3310
strand strand 3313 3315
strand strand 3317 3323
strand strand 3326 3333
strand strand 3340 3343
strand strand 3351 3358
strand strand 3361 3369
helix helix 3379 3381
strand strand 3388 3393
strand strand 3396 3406
turn turn 3408 3410
strand strand 3412 3415
strand strand 3421 3424
strand strand 3427 3430
helix helix 3441 3453
turn turn 3458 3460
helix helix 3467 3476
strand strand 3477 3479
helix helix 3484 3489
helix helix 3491 3497
helix helix 3501 3514
strand strand 3516 3518
strand strand 3521 3523
strand strand 3524 3526
helix helix 3533 3539
turn turn 3540 3542
helix helix 3837 3855
helix helix 3858 3860
helix helix 3862 3876
strand strand 3878 3880
helix helix 3881 3905
helix helix 3906 3909
turn turn 3910 3912
helix helix 3913 3916
helix helix 3922 3924
helix helix 3929 3946
helix helix 3951 3956
turn turn 3959 3963
turn turn 3970 3972
helix helix 3973 3987
helix helix 3996 4017
helix helix 4020 4030
strand strand 4034 4037
strand strand 4046 4051
helix helix 4054 4060
strand strand 4065 4068
strand strand 4071 4079
helix helix 4088 4090
turn turn 4093 4095
helix helix 4096 4098
strand strand 4103 4109
strand strand 4120 4125
strand strand 4127 4131
strand strand 4134 4137
strand strand 4145 4150
strand strand 4153 4155
strand strand 4157 4164
strand strand 4170 4174
strand strand 4181 4186
strand strand 4191 4194
strand strand 4201 4208
helix helix 4213 4222
helix helix 4224 4227
helix helix 4238 4240
helix helix 4243 4248
strand strand 4250 4252
helix helix 4253 4262
strand strand 4284 4288
strand strand 4295 4300
helix helix 4301 4303
helix helix 4305 4308
strand strand 4314 4318
strand strand 4325 4330
helix helix 4331 4333
helix helix 4337 4343
turn turn 4348 4350
strand strand 4351 4353
turn turn 4354 4357
strand strand 4490 4492
helix helix 4493 4501
strand strand 4505 4507
helix helix 4509 4517
helix helix 4523 4527
turn turn 4529 4532
strand strand 4534 4537
helix helix 4540 4544
helix helix 4545 4547
helix helix 4548 4567
strand strand 4570 4573
helix helix 4576 4578
strand strand 4600 4602
helix helix 4604 4616
turn turn 4617 4620
helix helix 4621 4624
helix helix 4645 4655
helix helix 4667 4669
strand strand 4671 4673
helix helix 4674 4686
helix helix 4687 4689
helix helix 4692 4694
strand strand 4695 4704
strand strand 4707 4717
turn turn 4718 4720
strand strand 4721 4724
strand strand 4731 4734
helix helix 4737 4744
helix helix 4748 4751
strand strand 4754 4759
strand strand 4766 4770
helix helix 4786 4793
turn turn 4794 4798
helix helix 4818 4822
helix helix 4823 4827
helix helix 4835 4847
turn turn 4848 4851
helix helix 4859 4861
helix helix 4875 4877
helix helix 4881 4885
helix helix 4890 4899
turn turn 4900 4902
strand strand 4908 4913
strand strand 4918 4920
strand strand 4925 4928
helix helix 4931 4949
strand strand 4953 4956
turn turn 4963 4965
helix helix 4966 4975
strand strand 4979 4985
helix helix 4991 4994
helix helix 4997 5007
helix helix 5008 5010
strand strand 5012 5014
helix helix 5017 5031
strand strand 5035 5038
strand strand 5041 5044
strand strand 5053 5055
helix helix 5056 5077
helix helix 5081 5083
helix helix 5087 5097
turn turn 5098 5100
helix helix 5108 5121
strand strand 5122 5127
strand strand 5130 5136
helix helix 5137 5140
turn turn 5141 5143
helix helix 5148 5158
helix helix 5165 5167
strand strand 5169 5171
strand strand 5184 5190
strand strand 5192 5200
helix helix 5203 5211
strand strand 5217 5219
helix helix 5221 5234
helix helix 5236 5240
helix helix 5244 5263
helix helix 5278 5282
helix helix 5283 5285
turn turn 5307 5309
strand strand 5312 5314
strand strand 5316 5320
helix helix 5328 5335
strand strand 5343 5349
helix helix 5361 5363
strand strand 5368 5372
turn turn 5374 5376
strand strand 5382 5386
turn turn 5393 5397
helix helix 5404 5412
helix helix 5418 5426
helix helix 5429 5446
helix helix 5447 5449
strand strand 5453 5457
strand strand 5461 5468
strand strand 5483 5488
strand strand 5493 5503
strand strand 5509 5516
strand strand 5525 5528
helix helix 5561 5566
helix helix 5567 5570
helix helix 5572 5575
strand strand 5576 5581
helix helix 5589 5599
strand strand 5605 5610
helix helix 5612 5616
turn turn 5617 5622
strand strand 5623 5626
strand strand 5630 5633
strand strand 5640 5642
strand strand 5647 5649
strand strand 5655 5660
turn turn 5661 5663
strand strand 5666 5668
strand strand 5670 5674
helix helix 5677 5679
helix helix 5682 5691
strand strand 5695 5700
helix helix 5720 5722
helix helix 5725 5730
strand strand 5743 5745
helix helix 5747 5750
turn turn 5751 5754
turn turn 5756 5759
turn turn 5791 5793
helix helix 5794 5796
turn turn 5797 5800
strand strand 5815 5818
turn turn 5819 5827
turn turn 5834 5836
strand strand 5843 5848
turn turn 5854 5856
helix helix 5859 5866
strand strand 5873 5876
helix helix 5882 5884
strand strand 5893 5895
strand strand 5922 5924
strand strand 5928 5931
helix helix 5933 5935
strand strand 5955 5957
helix helix 5978 5983
strand strand 5986 5997
strand strand 6000 6002
strand strand 6006 6016
strand strand 6018 6020
strand strand 6024 6028
strand strand 6033 6037
helix helix 6046 6053
helix helix 6054 6057
helix helix 6061 6076
turn turn 6077 6079
strand strand 6084 6089
helix helix 6091 6100
strand strand 6112 6115
strand strand 6118 6120
turn turn 6121 6124
strand strand 6125 6127
turn turn 6129 6131
strand strand 6137 6140
strand strand 6142 6145
helix helix 6146 6149
helix helix 6155 6162
strand strand 6164 6166
helix helix 6172 6188
helix helix 6204 6226
strand strand 6229 6235
strand strand 6242 6245
strand strand 6247 6256
strand strand 6263 6267
helix helix 6272 6275
turn turn 6276 6278
strand strand 6281 6288
strand strand 6296 6303
strand strand 6312 6314
strand strand 6320 6322
strand strand 6324 6326
strand strand 6328 6330
helix helix 6335 6338
strand strand 6341 6343
strand strand 6373 6376
strand strand 6381 6383
helix helix 6387 6405
strand strand 6408 6412
helix helix 6419 6425
helix helix 6431 6441
strand strand 6453 6456
strand strand 6459 6464
strand strand 6467 6473
strand strand 6476 6478
helix helix 6480 6488
strand strand 6493 6495
helix helix 6498 6503
strand strand 6508 6513
turn turn 6517 6520
strand strand 6521 6530
turn turn 6532 6534
strand strand 6535 6539
helix helix 6543 6545
strand strand 6550 6553
helix helix 6559 6565
strand strand 6567 6575
strand strand 6589 6591
strand strand 6594 6596
strand strand 6599 6601
strand strand 6606 6611
strand strand 6614 6616
helix helix 6629 6631
helix helix 6637 6644
helix helix 6647 6653
helix helix 6661 6664
strand strand 6670 6673
strand strand 6677 6679
helix helix 6680 6689
strand strand 6692 6698
strand strand 6703 6711
turn turn 6712 6714
strand strand 6717 6724
helix helix 6728 6736
strand strand 6741 6751
strand strand 6754 6763
strand strand 6766 6772
helix helix 6777 6780
strand strand 6781 6785
helix helix 6788 6791
helix helix 6817 6829
strand strand 6841 6846
helix helix 6855 6863
strand strand 6869 6876
strand strand 6881 6888
helix helix 6890 6892
strand strand 6893 6897
strand strand 6899 6904
helix helix 6924 6935
strand strand 6936 6946
strand strand 6948 6950
helix helix 6953 6959
strand strand 6962 6970
helix helix 6971 6973
strand strand 6979 6986
helix helix 6996 7009
helix helix 7017 7020
strand strand 7033 7035
helix helix 7039 7041
helix helix 7044 7051
strand strand 7055 7057
strand strand 7065 7067
chain Host translation inhibitor nsp1 (PRO_0000037309) 1 180
chain Non-structural protein 2 (PRO_0000037310) 181 818
chain Non-structural protein 3 (PRO_0000037311) 819 2740
chain Non-structural protein 4 (PRO_0000283841) 2741 3240
chain 3C-like proteinase (PRO_0000037312) 3241 3546
chain Non-structural protein 6 (PRO_0000037313) 3547 3836
chain Non-structural protein 7 (PRO_0000037314) 3837 3919
chain Non-structural protein 8 (PRO_0000037315) 3920 4117
chain Non-structural protein 9 (PRO_0000037316) 4118 4230
chain Non-structural protein 10 (PRO_0000037317) 4231 4369
chain RNA-directed RNA polymerase (PRO_0000037318) 4370 5301
chain Helicase (PRO_0000037319) 5302 5902
chain Proofreading exoribonuclease (PRO_0000037320) 5903 6429
chain Uridylate-specific endoribonuclease (PRO_0000037321) 6430 6775
chain 2'-O-methyltransferase (PRO_0000037322) 6776 7073
topological domain Cytoplasmic 1 2202
transmembrane region Helical 2203 2223
topological domain Lumenal 2224 2303
transmembrane region Helical 2304 2324
topological domain Cytoplasmic 2325 2350
transmembrane region Helical 2351 2371
topological domain Lumenal 2372 2754
transmembrane region Helical 2755 2775
topological domain Cytoplasmic 2776 2991
transmembrane region Helical 2992 3012
topological domain Lumenal 3013 3021
transmembrane region Helical 3022 3042
topological domain Cytoplasmic 3043 3053
transmembrane region Helical 3054 3074
topological domain Lumenal 3075 3076
transmembrane region Helical 3077 3097
topological domain Cytoplasmic 3098 3104
transmembrane region Helical 3105 3125
topological domain Lumenal 3126 3141
transmembrane region Helical 3142 3162
topological domain Cytoplasmic 3163 3563
transmembrane region Helical 3564 3584
topological domain Lumenal 3585 3585
transmembrane region Helical 3586 3606
topological domain Cytoplasmic 3607 3611
transmembrane region Helical 3612 3632
topological domain Lumenal 3633 3657
transmembrane region Helical 3658 3678
topological domain Cytoplasmic 3679 3684
transmembrane region Helical 3685 3704
topological domain Lumenal 3705 3727
transmembrane region Helical 3728 3748
topological domain Cytoplasmic 3749 3755
transmembrane region Helical 3756 3776
topological domain Lumenal 3777 7073
Other domain of interest Macro 1003 1169
Other domain of interest Peptidase C16 1611 1875
Other domain of interest Peptidase C30 3241 3546
Other domain of interest RdRp catalytic 4981 5143
Other domain of interest CV ZBD 5302 5385
Other domain of interest (+)RNA virus helicase ATP-binding 5558 5739
Other domain of interest (+)RNA virus helicase C-terminal 5740 5909
zinc finger region C4-type 1729 1766
zinc finger region zinc finger region 4304 4320
zinc finger region zinc finger region 4347 4360
Nucleotide-binding region ATP 5583 5590
region of interest HD1 2092 2371
region of interest HD2 2755 3162
region of interest HD3 3564 3776
compositionally biased region Glu-rich 930 1001
compositionally biased region Poly-Leu 2210 2213
compositionally biased region Poly-Cys 3766 3769
active site For PL-PRO activity 1651 1651
active site For PL-PRO activity 1812 1812
active site For 3CL-PRO activity 3281 3281
active site For 3CL-PRO activity 3385 3385
metal ion-binding site Zinc 4304 4304
metal ion-binding site Zinc 4307 4307
metal ion-binding site Zinc 4313 4313
metal ion-binding site Zinc 4320 4320
metal ion-binding site Zinc 4347 4347
metal ion-binding site Zinc 4350 4350
metal ion-binding site Zinc 4358 4358
metal ion-binding site Zinc 1 5306 5306
metal ion-binding site Zinc 1 5309 5309
metal ion-binding site Zinc 2 5317 5317
metal ion-binding site Zinc 1 5320 5320
metal ion-binding site Zinc 1 5327 5327
metal ion-binding site Zinc 2 5330 5330
metal ion-binding site Zinc 2 5334 5334
metal ion-binding site Zinc 2 5340 5340
metal ion-binding site Zinc 3 5351 5351
metal ion-binding site Zinc 3 5356 5356
metal ion-binding site Zinc 3 5373 5373
metal ion-binding site Zinc 3 5376 5376
Other site of interest Cleavage 180 181
Other site of interest Cleavage; by PL-PRO 818 819
Other site of interest Cleavage; by PL-PRO 2740 2741
Other site of interest Cleavage; by 3CL-PRO 3240 3241
Other site of interest Cleavage; by 3CL-PRO 3546 3547
Other site of interest Cleavage; by 3CL-PRO 3836 3837
Other site of interest Cleavage; by 3CL-PRO 3919 3920
Other site of interest Cleavage; by 3CL-PRO 4117 4118
Other site of interest Cleavage; by 3CL-PRO 4230 4231
Other site of interest Cleavage; by 3CL-PRO 4369 4370
Other site of interest Cleavage; by 3CL-PRO 5301 5302
Other site of interest Cleavage; by 3CL-PRO 5902 5903
Other site of interest Cleavage; by 3CL-PRO 6429 6430
Other site of interest Cleavage; by 3CL-PRO 6775 6776
Sequence variation in strain: Isolate GD01 () 82 82
Sequence variation in strain: Isolate GD01 () 130 130
Sequence variation in strain: Isolate SZ16 () 138 138
Sequence variation in strain: Isolate Shanghai LY () 181 181
Sequence variation in strain: Isolate GD01 () 225 225
Sequence variation in strain: Isolate Shanghai LY () 249 249
Sequence variation in strain: Isolate BJ04 () 306 306
Sequence variation in strain: Isolate SZ3 () 549 549
Sequence variation in strain: Isolate FRA and Isolate Frankfurt-1 () 765 765
Sequence variation in strain: Isolate SZ16 () 852 852
Sequence variation in strain: Isolate BJ03 () 1004 1004
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1021 1021
Sequence variation in strain: Isolate Shanghai QXC1 () 1023 1023
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 1121 1121
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1136 1136
Sequence variation in strain: Isolate Shanghai QXC1 () 1257 1257
Sequence variation in strain: Isolate GD01 () 1319 1319
Sequence variation in strain: Isolate GD01 () 1329 1329
Sequence variation in strain: Isolate Shanghai QXC1 () 1361 1361
Sequence variation in strain: Isolate Shanghai QXC1 () 1385 1385
Sequence variation in strain: Isolate GD01 () 1538 1538
Sequence variation in strain: Isolate BJ02 () 1563 1563
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 1663 1663
Sequence variation in strain: Isolate BJ03 () 1762 1762
Sequence variation in strain: Isolate BJ03 () 1776 1777
Sequence variation in strain: Isolate Shanghai QXC1 () 1790 1790
Sequence variation in strain: Isolate BJ02 () 1806 1806
Sequence variation in strain: Isolate BJ04 () 1962 1962
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 2116 2116
Sequence variation in strain: Isolate GD01, Isolate SZ3 and Isolate SZ16 () 2222 2222
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 2269 2269
Sequence variation in strain: Isolate Shanghai QXC1 () 2326 2326
Sequence variation in strain: Isolate Shanghai QXC1 () 2392 2394
Sequence variation in strain: Isolate Shanghai QXC1 () 2480 2480
Sequence variation in strain: Isolate Urbani and Isolate Taiwan TC2 () 2552 2552
Sequence variation in strain: Isolate HKU-39849 () 2556 2556
Sequence variation in strain: Isolate GD01 () 2564 2564
Sequence variation in strain: Isolate Shanghai QXC1 () 2648 2648
Sequence variation in strain: Isolate HKU-39849 () 2708 2708
Sequence variation in strain: Isolate HKU-39849 () 2718 2718
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 2746 2746
Sequence variation in strain: Isolate BJ01 and Isolate BJ02 () 2770 2770
Sequence variation in strain: Isolate SIN2500, Isolate GD01 and Isolate GZ50 () 2944 2944
Sequence variation in strain: Isolate GD01 and Isolate SZ16 () 2971 2971
Sequence variation in strain: Isolate Shanghai QXC1 () 3020 3020
Sequence variation in strain: Isolate CUHK-W1, Isolate GD01, Isolate SZ3, Isolate S () 3047 3047
Sequence variation in strain: Isolate CUHK-W1, Isolate SZ3, Isolate SZ16 and Isolat () 3072 3072
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate BJ0 () 3197 3197
Sequence variation in strain: Isolate BJ02 () 3429 3429
Sequence variation in strain: Isolate BJ04 () 3488 3488
Sequence variation in strain: Isolate Shanghai QXC1 () 3717 3717
Sequence variation in strain: Isolate BJ04 () 3818 3818
Sequence variation in strain: Isolate BJ03 () 3903 3903
Sequence variation in strain: Isolate BJ02 () 3904 3904
Sequence variation in strain: Isolate Shanghai QXC1 () 3911 3911
Sequence variation in strain: Isolate Shanghai LY () 4001 4001
Sequence variation in strain: Isolate Shanghai LY () 4003 4003
Sequence variation in strain: Isolate ZJ01 () 4085 4085
Sequence variation in strain: Isolate Shanghai QXC1 () 4114 4114
Sequence variation in strain: Isolate Shanghai QXC1 () 4202 4202
Sequence variation in strain: Isolate ZJ01 () 4240 4240
Sequence variation in strain: Isolate Shanghai QXC1 () 4296 4296
helix helix 3294 3299
Sequence variation in strain: Isolate Shanghai QXC1 () 4377 4378
Sequence variation in strain: Isolate HKU-39849 () 4411 4411
Sequence variation in strain: Isolate Shanghai QXC1 () 4459 4459
Sequence variation in strain: Isolate ZJ01 () 4592 4592
Sequence variation in strain: Isolate ZJ01 () 4910 4910
Sequence variation in strain: Isolate SZ3 () 5112 5112
Sequence variation in strain: Isolate Taiwan () 5131 5131
Sequence variation in strain: Isolate Taiwan () 5134 5135
Sequence variation in strain: Isolate GD01 () 5623 5623
Sequence variation in strain: Isolate GZ50 and Isolate SIN2500 () 5720 5720
Sequence variation in strain: Isolate ZJ01 () 5744 5744
Sequence variation in strain: Isolate CUHK-W1, Isolate BJ01, Isolate BJ02, Isolate () 5767 5767
Sequence variation in strain: Isolate FRA, Isolate Frankfurt-1 Isolate SIN2677, Iso () 6274 6274
Sequence variation in strain: Isolate Shanghai QXC1 () 6474 6474
Sequence variation in strain: Isolate BJ03 () 6700 6700
Sequence variation in strain: Isolate Shanghai QXC1 () 6721 6721
Sequence variation in strain: Isolate GD01 () 6729 6729
Sequence variation in strain: Isolate BJ02 () 6840 6840
Sequence variation in strain: Isolate BJ04 () 6862 6862
Sequence variation in strain: Isolate GD01 () 6877 6877
Sequence variation in strain: Isolate SZ3 and Isolate SZ16 () 6910 6910
Sequence variation in strain: Isolate BJ03 () 6937 6937
Sequence variation in strain: Isolate BJ04 () 6992 6992
Sequence variation in strain: Isolate GD01 () 7008 7008
Sequence variation in strain: Isolate BJ04 () 7024 7024
mutagenesis site Complete loss of nsp9 dimerization. 4217 4217
mutagenesis site Complete loss of nsp9 dimerization. 4221 4221
strand strand 14 20
turn turn 23 25
helix helix 35 48
strand strand 51 54
helix helix 61 63
strand strand 68 72
strand strand 87 93
turn turn 95 98
strand strand 99 102
strand strand 105 109
strand strand 116 123
strand strand 827 829
turn turn 831 833
strand strand 839 841
strand strand 848 851
turn turn 852 856
strand strand 860 862
turn turn 869 871
helix helix 872 882
helix helix 888 894
helix helix 898 901
strand strand 907 909
strand strand 911 915
strand strand 918 920
strand strand 922 926
strand strand 1013 1021
helix helix 1023 1030
strand strand 1033 1038
helix helix 1048 1056
turn turn 1057 1059
helix helix 1060 1072
strand strand 1080 1084
turn turn 1086 1088
strand strand 1090 1095
helix helix 1100 1102
helix helix 1108 1114
helix helix 1115 1118
strand strand 1119 1124
helix helix 1130 1132
helix helix 1136 1146
strand strand 1149 1156
helix helix 1158 1168
strand strand 1345 1347
helix helix 1351 1361
strand strand 1364 1368
helix helix 1372 1381
strand strand 1389 1401
helix helix 1407 1417
strand strand 1421 1424
strand strand 1426 1428
helix helix 1429 1431
helix helix 1435 1442
strand strand 1449 1452
helix helix 1457 1467
strand strand 1544 1555
strand strand 1557 1562
helix helix 1567 1571
strand strand 1572 1576
strand strand 1582 1584
helix helix 1588 1590
strand strand 1594 1597
helix helix 1602 1612
helix helix 1619 1630
strand strand 1639 1642
turn turn 1648 1650
helix helix 1651 1661
strand strand 1667 1669
helix helix 1670 1680
helix helix 1685 1694
helix helix 1705 1713
strand strand 1722 1728
strand strand 1730 1732
strand strand 1734 1740
helix helix 1742 1745
strand strand 1746 1749
helix helix 1753 1758
strand strand 1760 1763
strand strand 1765 1785
strand strand 1790 1793
helix helix 1795 1797
strand strand 1799 1807
strand strand 1810 1826
strand strand 1829 1834
strand strand 1836 1846
strand strand 1904 1911
helix helix 1912 1921
strand strand 1929 1936
strand strand 1942 1948
helix helix 1949 1951
helix helix 1954 1956
strand strand 1963 1966
strand strand 1969 1971
helix helix 1977 1990
helix helix 3251 3254
strand strand 3257 3262
strand strand 3265 3272
strand strand 3275 3279
helix helix 3280 3283
helix helix 3286 3290
helix helix 3303 3305
strand strand 3307 3310
strand strand 3313 3315
strand strand 3317 3323
strand strand 3326 3333
strand strand 3340 3343
strand strand 3351 3358
strand strand 3361 3369
helix helix 3379 3381
strand strand 3388 3393
strand strand 3396 3406
turn turn 3408 3410
strand strand 3412 3415
strand strand 3421 3424
strand strand 3427 3430
helix helix 3441 3453
turn turn 3458 3460
helix helix 3467 3476
strand strand 3477 3479
helix helix 3484 3489
helix helix 3491 3497
helix helix 3501 3514
strand strand 3516 3518
strand strand 3521 3523
strand strand 3524 3526
helix helix 3533 3539
turn turn 3540 3542
helix helix 3837 3855
helix helix 3858 3860
helix helix 3862 3876
strand strand 3878 3880
helix helix 3881 3905
helix helix 3906 3909
turn turn 3910 3912
helix helix 3913 3916
helix helix 3922 3924
helix helix 3929 3946
helix helix 3951 3956
turn turn 3959 3963
turn turn 3970 3972
helix helix 3973 3987
helix helix 3996 4017
helix helix 4020 4030
strand strand 4034 4037
strand strand 4046 4051
helix helix 4054 4060
strand strand 4065 4068
strand strand 4071 4079
helix helix 4088 4090
turn turn 4093 4095
helix helix 4096 4098
strand strand 4103 4109
strand strand 4120 4125
strand strand 4127 4131
strand strand 4134 4137
strand strand 4145 4150
strand strand 4153 4155
strand strand 4157 4164
strand strand 4170 4174
strand strand 4181 4186
strand strand 4191 4194
strand strand 4201 4208
helix helix 4213 4222
helix helix 4224 4227
helix helix 4238 4240
helix helix 4243 4248
strand strand 4250 4252
helix helix 4253 4262
strand strand 4284 4288
strand strand 4295 4300
helix helix 4301 4303
helix helix 4305 4308
strand strand 4314 4318
strand strand 4325 4330
helix helix 4331 4333
helix helix 4337 4343
turn turn 4348 4350
strand strand 4351 4353
turn turn 4354 4357
strand strand 4490 4492
helix helix 4493 4501
strand strand 4505 4507
helix helix 4509 4517
helix helix 4523 4527
turn turn 4529 4532
strand strand 4534 4537
helix helix 4540 4544
helix helix 4545 4547
helix helix 4548 4567
strand strand 4570 4573
helix helix 4576 4578
strand strand 4600 4602
helix helix 4604 4616
turn turn 4617 4620
helix helix 4621 4624
helix helix 4645 4655
helix helix 4667 4669
strand strand 4671 4673
helix helix 4674 4686
helix helix 4687 4689
helix helix 4692 4694
strand strand 4695 4704
strand strand 4707 4717
turn turn 4718 4720
strand strand 4721 4724
strand strand 4731 4734
helix helix 4737 4744
helix helix 4748 4751
strand strand 4754 4759
strand strand 4766 4770
helix helix 4786 4793
turn turn 4794 4798
helix helix 4818 4822
helix helix 4823 4827
helix helix 4835 4847
turn turn 4848 4851
helix helix 4859 4861
helix helix 4875 4877
helix helix 4881 4885
helix helix 4890 4899
turn turn 4900 4902
strand strand 4908 4913
strand strand 4918 4920
strand strand 4925 4928
helix helix 4931 4949
strand strand 4953 4956
turn turn 4963 4965
helix helix 4966 4975
strand strand 4979 4985
helix helix 4991 4994
helix helix 4997 5007
helix helix 5008 5010
strand strand 5012 5014
helix helix 5017 5031
strand strand 5035 5038
strand strand 5041 5044
strand strand 5053 5055
helix helix 5056 5077
helix helix 5081 5083
helix helix 5087 5097
turn turn 5098 5100
helix helix 5108 5121
strand strand 5122 5127
strand strand 5130 5136
helix helix 5137 5140
turn turn 5141 5143
helix helix 5148 5158
helix helix 5165 5167
strand strand 5169 5171
strand strand 5184 5190
strand strand 5192 5200
helix helix 5203 5211
strand strand 5217 5219
helix helix 5221 5234
helix helix 5236 5240
helix helix 5244 5263
helix helix 5278 5282
helix helix 5283 5285
turn turn 5307 5309
strand strand 5312 5314
strand strand 5316 5320
helix helix 5328 5335
strand strand 5343 5349
helix helix 5361 5363
strand strand 5368 5372
turn turn 5374 5376
strand strand 5382 5386
turn turn 5393 5397
helix helix 5404 5412
helix helix 5418 5426
helix helix 5429 5446
helix helix 5447 5449
strand strand 5453 5457
strand strand 5461 5468
strand strand 5483 5488
strand strand 5493 5503
strand strand 5509 5516
strand strand 5525 5528
helix helix 5561 5566
helix helix 5567 5570
helix helix 5572 5575
strand strand 5576 5581
helix helix 5589 5599
strand strand 5605 5610
helix helix 5612 5616
turn turn 5617 5622
strand strand 5623 5626
strand strand 5630 5633
strand strand 5640 5642
strand strand 5647 5649
strand strand 5655 5660
turn turn 5661 5663
strand strand 5666 5668
strand strand 5670 5674
helix helix 5677 5679
helix helix 5682 5691
strand strand 5695 5700
helix helix 5720 5722
helix helix 5725 5730
strand strand 5743 5745
helix helix 5747 5750
turn turn 5751 5754
turn turn 5756 5759
turn turn 5791 5793
helix helix 5794 5796
turn turn 5797 5800
strand strand 5815 5818
turn turn 5819 5827
turn turn 5834 5836
strand strand 5843 5848
turn turn 5854 5856
helix helix 5859 5866
strand strand 5873 5876
helix helix 5882 5884
strand strand 5893 5895
strand strand 5922 5924
strand strand 5928 5931
helix helix 5933 5935
strand strand 5955 5957
helix helix 5978 5983
strand strand 5986 5997
strand strand 6000 6002
strand strand 6006 6016
strand strand 6018 6020
strand strand 6024 6028
strand strand 6033 6037
helix helix 6046 6053
helix helix 6054 6057
helix helix 6061 6076
turn turn 6077 6079
strand strand 6084 6089
helix helix 6091 6100
strand strand 6112 6115
strand strand 6118 6120
turn turn 6121 6124
strand strand 6125 6127
turn turn 6129 6131
strand strand 6137 6140
strand strand 6142 6145
helix helix 6146 6149
helix helix 6155 6162
strand strand 6164 6166
helix helix 6172 6188
helix helix 6204 6226
strand strand 6229 6235
strand strand 6242 6245
strand strand 6247 6256
strand strand 6263 6267
helix helix 6272 6275
turn turn 6276 6278
strand strand 6281 6288
strand strand 6296 6303
strand strand 6312 6314
strand strand 6320 6322
strand strand 6324 6326
strand strand 6328 6330
helix helix 6335 6338
strand strand 6341 6343
strand strand 6373 6376
strand strand 6381 6383
helix helix 6387 6405
strand strand 6408 6412
helix helix 6419 6425
helix helix 6431 6441
strand strand 6453 6456
strand strand 6459 6464
strand strand 6467 6473
strand strand 6476 6478
helix helix 6480 6488
strand strand 6493 6495
helix helix 6498 6503
strand strand 6508 6513
turn turn 6517 6520
strand strand 6521 6530
turn turn 6532 6534
strand strand 6535 6539
helix helix 6543 6545
strand strand 6550 6553
helix helix 6559 6565
strand strand 6567 6575
strand strand 6589 6591
strand strand 6594 6596
strand strand 6599 6601
strand strand 6606 6611
strand strand 6614 6616
helix helix 6629 6631
helix helix 6637 6644
helix helix 6647 6653
helix helix 6661 6664
strand strand 6670 6673
strand strand 6677 6679
helix helix 6680 6689
strand strand 6692 6698
strand strand 6703 6711
turn turn 6712 6714
strand strand 6717 6724
helix helix 6728 6736
strand strand 6741 6751
strand strand 6754 6763
strand strand 6766 6772
helix helix 6777 6780
strand strand 6781 6785
helix helix 6788 6791
helix helix 6817 6829
strand strand 6841 6846
helix helix 6855 6863
strand strand 6869 6876
strand strand 6881 6888
helix helix 6890 6892
strand strand 6893 6897
strand strand 6899 6904
helix helix 6924 6935
strand strand 6936 6946
strand strand 6948 6950
helix helix 6953 6959
strand strand 6962 6970
helix helix 6971 6973
strand strand 6979 6986
helix helix 6996 7009
helix helix 7017 7020
strand strand 7033 7035
helix helix 7039 7041
helix helix 7044 7051
strand strand 7055 7057
strand strand 7065 7067

Secuencia AA

Contexto Génico

Variantes

PosRefAltPaísesInfo.
224 T I Mexico:1 Mapeado en 0 estructuras.
265 T I Brazil:2 Mapeado en 0 estructuras.
348 N S Mexico:1 Mapeado en 0 estructuras.
378 V I Brazil:1 Mapeado en 0 estructuras.
392 G D Brazil:1 Mapeado en 0 estructuras.
609 T I Brazil:1 Mapeado en 0 estructuras.
708 T I Brazil:3 Mapeado en 0 estructuras.
739 I V Brazil:1 Mapeado en 0 estructuras.
765 P S Brazil:2 Mapeado en 0 estructuras.
876 A T Brazil:1 Mapeado en 2 estructuras.
889 L F Mexico:1 Mapeado en 2 estructuras.
892 P L Mexico:1 Mapeado en 5 estructuras.
En regiones de interés tipo: FPocketPocket
944 S L Uruguay:1 Mapeado en 0 estructuras.
1036 D E Brazil:1 Mapeado en 2 estructuras.
En regiones de interés tipo: BINDING SITE
1043 A V Chile:1 Mapeado en 2 estructuras.
En regiones de interés tipo: BINDING SITE - FPocketPocket
1246 T I Brazil:1 Mapeado en 0 estructuras.
1249 L F Ecuador:1 Mapeado en 0 estructuras.
1599 L F Brazil:1 Mapeado en 4 estructuras.
1798 V E Brazil:1 Mapeado en 3 estructuras.
En regiones de interés tipo: FPocketPocket
2016 T K Brazil:1 Mapeado en 1 estructuras.
2193 S T Mexico:1 Mapeado en 0 estructuras.
2384 Y - Brazil:1 Mapeado en 0 estructuras.
2387 F L Brazil:1 Mapeado en 0 estructuras.
2457 T K Uruguay:1 Mapeado en 0 estructuras.
3071 F Y Brazil:3 Chile:4 Mexico:1 Mapeado en 0 estructuras.
3108 I T Brazil:1 Mapeado en 0 estructuras.
3334 G S Brazil:1 Mapeado en 54 estructuras.
En regiones de interés tipo: FPocketPocket
3570 S R Brazil:1 Mapeado en 1 estructuras.
3606 L F Brazil:5 Uruguay:1 Mexico:1 Mapeado en 0 estructuras.
3930 L F Brazil:1 Mapeado en 4 estructuras.
En regiones de interés tipo: FPocketPocket
4401 N insA Brazil:63 Chile:7 Colombia:2 Ecuador:2 Uruguay:8 Mexico:15 Panama:1 Mapeado en 0 estructuras.
4401 N insF Brazil:63 Chile:7 Colombia:2 Ecuador:2 Uruguay:8 Mexico:15 Panama:1 Mapeado en 0 estructuras.
4401 N insG Brazil:63 Chile:7 Colombia:2 Ecuador:2 Uruguay:8 Mexico:15 Panama:1 Mapeado en 0 estructuras.
4401 N insV Brazil:63 Chile:7 Colombia:2 Ecuador:2 Uruguay:8 Mexico:15 Panama:1 Mapeado en 0 estructuras.
4401 N insX Brazil:5 Mapeado en 0 estructuras.
4455 D Y Uruguay:1 Mapeado en 0 estructuras.
4489 A V Brazil:1 Mapeado en 0 estructuras.
4619 P L Brazil:1 Mapeado en 2 estructuras.
4715 P L Brazil:58 Chile:1 Colombia:1 Ecuador:1 Mexico:7 Panama:1 Mapeado en 2 estructuras.
5028 L I Brazil:1 Mapeado en 2 estructuras.
5209 T R Brazil:1 Mapeado en 2 estructuras.
5381 V D Brazil:1 Mapeado en 1 estructuras.
5792 S L Mexico:1 Mapeado en 1 estructuras.
5828 P L Uruguay:1 Mexico:5 Mapeado en 1 estructuras.
5865 Y C Uruguay:1 Mexico:5 Mapeado en 1 estructuras.
5894 V L Uruguay:1 Mapeado en 1 estructuras.
6044 A G Brazil:1 Mapeado en 4 estructuras.
6062 S I Brazil:1 Mapeado en 4 estructuras.
6137 R S Brazil:1 Mapeado en 4 estructuras.
En regiones de interés tipo: FPocketPocket
6164 P A Mexico:1 Mapeado en 4 estructuras.
En regiones de interés tipo: FPocketPocket
6215 V F Chile:1 Mapeado en 4 estructuras.
En regiones de interés tipo: FPocketPocket
6831 S G Brazil:1 Mapeado en 4 estructuras.
En regiones de interés tipo: FPocketPocket
7096 N insX Brazil:10 Mapeado en 1 estructuras.
En regiones de interés tipo: FPocketPocket