S

Spike glycoprotein

Función

Biological Process

Molecular Function/s

Localización Celular

Keywords Uniprot

DBIdentificador
EMBL AY323977
Proteomes UP000131569
EMBL AY304486
Proteomes UP000138690
EMBL AY283794
InterPro IPR043473
UnipAcc Q7TA19
UnipAcc Q80BV6
EMBL AY278741
RefSeq NP_828851.1
EMBL AY463059
EMBL AY427439
EMBL AY278491
SMR P59594
EMBL AP006561
Pfam PF01601
EMBL AY283798
EMBL AY278490
BioGRID 4383915
InterPro IPR032500
EMBL AY323976
UnipGene S
EMBL AY274119
DIP DIP-29105N
Proteomes UP000137377
EMBL AY304492
Proteomes UP000145651
EMBL AP006559
InterPro IPR027400
InterPro IPR018548
UnipAcc P59594
ComplexPortal CPX-5694
Proteomes UP000121636
InterPro IPR042578
EMBL AY291315
EMBL AY362698
PROSITE PS51923
KO K24152
EMBL AY278554
EMBL AY278488
ABCD P59594
Proteomes UP000146181
Proteomes UP000146108
Proteomes UP000172416
PROSITE PS51921
UnipAcc Q7TFA2
EMBL AP006560
SIGNOR P59594
GeneID 1489668
EMBL AY278487
SUPFAM SSF111474
Proteomes UP000103670
EMBL AP006557
Pfam PF09408
EMBL AY283797
Proteomes UP000131955
UnipAcc Q7TFB1
Proteomes UP000164441
EMBL AY304495
GlyGen P59594
PRIDE P59594
UnipAcc Q6QU82
Proteomes UP000148194
EMBL AY322207
EMBL AY291451
Pfam PF16451
EMBL AY362699
EMBL AY282752
Proteomes UP000146296
EMBL AY278489
Gene3D 1.20.5.790
Proteomes UP000109640
UnipAcc Q7T696
EMBL AP006558
KEGG vg:1489668
Proteomes UP000000354
HAMAP MF_04099
InterPro IPR002552
UnipAcc SPIKE_SARS
EMBL AY283795
EMBL AY321118
EMBL AY338174
Proteomes UP000153467
EvolutionaryTrace P59594
Proteomes UP000143093
EMBL AY525636
EMBL AY310120
EMBL AY279354
Proteomes UP000116947
InterPro IPR036326
PROSITE PS51922
EMBL AY338175
SUPFAM SSF143587
EMBL AY283796
IntAct P59594
Proteomes UP000160648
EMBL AY348314

Estructura/s

TipoCodNombreDrogabilidad
PDB 1wyy VIRAL PROTEIN 0.296
PDB 6acj VIRAL PROTEIN/HYDROLASE 0.771
PDB 6cs2 viral protein/hydrolase 0.589
PDB 3scl HYDROLASE/VIRAL PROTEIN 0.795
PDB 6crx VIRAL PROTEIN 0.743
PDB 2beq VIRAL PROTEIN 0.876
PDB 6acg VIRAL PROTEIN/HYDROLASE 0.736
PDB 1zvb VIRAL PROTEIN 0.768
PDB 5xlr VIRAL PROTEIN 0.416
PDB 2ghv VIRAL PROTEIN 0.504
PDB 6crv VIRAL PROTEIN 0.46
PDB 3d0h HYDROLASE 0.853
PDB 3d0i HYDROLASE 0.721
PDB 5x4s VIRAL PROTEIN 0.61
PDB 6cs0 VIRAL PROTEIN
PDB 1zv7 VIRAL PROTEIN
PDB 6acd VIRAL PROTEIN 0.732
PDB 6nb6 VIRUS
PDB 3scj HYDROLASE/VIRAL PROTEIN 0.56
PDB 6waq VIRAL PROTEIN/IMMUNE SYSTEM 0.761
PDB 5x5b VIRAL PROTEIN 0.827
PDB 6ack VIRAL PROTEIN/HYDROLASE 0.85
PDB 2run VIRAL PROTEIN
PDB 2ghw VIRUS/VIRAL PROTEIN/ANTIBIOTIC 0.707
PDB 2rum VIRAL PROTEIN
PDB 6cs1 VIRAL PROTEIN 0.917
PDB 5x58 VIRAL PROTEIN 0.726
PDB 3bgf Viral Protein/Immune System 0.769
PDB 5wrg VIRUS LIKE PARTICLE 0.703
PDB 5xjk VIRAL PROTEIN 0.786
PDB 3sci HYDROLASE/VIRAL PROTEIN 0.575
PDB 6crz VIRAL PROTEIN
PDB 1wnc VIRAL PROTEIN 0.613
PDB 3sck HYDROLASE/VIRAL PROTEIN 0.794
PDB 6vw1 CELL INVASION 0.663
PDB 6nb7 VIRUS
PDB 6acc VIRAL PROTEIN 0.416
PDB 2fxp VIRAL PROTEIN 0.547
PDB 1zv8 VIRAL PROTEIN 0.734
PDB 2bez VIRAL PROTEIN
PDB 6crw VIRAL PROTEIN 0.52
PDB 2ajf hydrolase/viral protein 0.553
PDB 3d0g HYDROLASE 0.509
PDB 5zvm VIRAL PROTEIN/INHIBITOR
PDB 2dd8 IMMUNE SYSTEM/VIRAL PROTEIN 0.544
PDB 2ruo VIRAL PROTEIN

Anotación

Tipo Identificador InicioFin
signal peptide signal peptide 1 13
chain Spike glycoprotein (PRO_0000037208) 14 1255
chain Spike protein S1 (PRO_0000037209) 14 667
chain Spike protein S2 (PRO_0000037210) 668 1255
chain Spike protein S2' (PRO_0000444082) 798 1255
topological domain Extracellular 14 1195
transmembrane region Helical 1196 1216
topological domain Cytoplasmic 1217 1255
Other domain of interest BetaCoV S1-NTD 14 290
Other domain of interest BetaCoV S1-CTD 321 513
region of interest Receptor-binding domain 306 527
region of interest Receptor-binding motif; binding to human ACE2 424 494
region of interest Fusion peptide 1 798 819
region of interest Fusion peptide 2 817 837
region of interest Heptad repeat 1 902 952
region of interest Heptad repeat 2 1145 1184
coiled-coil region coiled-coil region 931 975
coiled-coil region coiled-coil region 1157 1185
short sequence motif KxHxx 1251 1255
compositionally biased region Cys-rich 1217 1236
Other site of interest Cleavage 667 668
Other site of interest Cleavage 797 798
glycosylation site N-linked (GlcNAc...) asparagine; by host () 29 29
glycosylation site N-linked (GlcNAc...) asparagine; by host () 65 65
glycosylation site N-linked (GlcNAc...) asparagine; by host () 73 73
glycosylation site N-linked (GlcNAc...) asparagine; by host () 109 109
glycosylation site N-linked (GlcNAc...) asparagine; by host () 118 118
glycosylation site N-linked (GlcNAc...) asparagine; by host () 119 119
glycosylation site N-linked (GlcNAc...) asparagine; by host () 158 158
glycosylation site N-linked (GlcNAc...) asparagine; by host () 227 227
glycosylation site N-linked (GlcNAc...) asparagine; by host () 269 269
glycosylation site N-linked (GlcNAc...) asparagine; by host () 318 318
glycosylation site N-linked (GlcNAc...) asparagine; by host () 330 330
glycosylation site N-linked (GlcNAc...) asparagine; by host () 357 357
glycosylation site N-linked (GlcNAc...) asparagine; by host () 589 589
glycosylation site N-linked (GlcNAc...) asparagine; by host () 602 602
glycosylation site N-linked (GlcNAc...) asparagine; by host () 691 691
glycosylation site N-linked (GlcNAc...) asparagine; by host () 699 699
glycosylation site N-linked (GlcNAc...) asparagine; by host () 783 783
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1056 1056
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1080 1080
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1116 1116
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1140 1140
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1155 1155
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1176 1176
disulfide bond disulfide bond 19 133
disulfide bond disulfide bond 128 159
disulfide bond disulfide bond 278 288
disulfide bond disulfide bond 323 348
disulfide bond disulfide bond 366 419
disulfide bond disulfide bond 378 511
disulfide bond disulfide bond 467 474
disulfide bond disulfide bond 822 833
Sequence variation in strain: Isolate GZ50 () 49 49
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate GZ5 () 77 77
Sequence variation in strain: Isolate GD03 () 78 78
Sequence variation in strain: Isolate Shanghai LY () 118 118
Sequence variation in strain: Isolate GD03 () 139 139
Sequence variation in strain: Isolate BJ03 () 144 144
Sequence variation in strain: Isolate GD03 () 147 147
Sequence variation in strain: Isolate Shanghai LY () 193 193
Sequence variation in strain: Isolate SZ3 () 227 227
Sequence variation in strain: Isolate GD01 and Isolate SZ3 () 239 239
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate BJ0 () 244 244
Sequence variation in strain: Isolate SZ3 () 261 261
Sequence variation in strain: Isolate GD01 and Isolate BJ02 () 311 311
Sequence variation in strain: Isolate GD01, Isolate GD03 and Isolate SZ3; no effect () 344 344
Sequence variation in strain: Isolate GD03 and Isolate SZ3; no effect on affinity w () 360 360
Sequence variation in strain: Isolate Shanghai LY () 426 426
Sequence variation in strain: Isolate Shanghai LY () 437 437
Sequence variation in strain: Isolate GD03 () 472 472
Sequence variation in strain: Isolate SZ3; 20fold decrease of affinity with human A () 479 479
Sequence variation in strain: Isolate GD03 () 480 480
Sequence variation in strain: Isolate GD03 and Isolate SZ3; 20fold decrease of affi () 487 487
Sequence variation in strain: Isolate GD01 () 501 501
Sequence variation in strain: Isolate Tor2 and Isolate Shanghai QXC1 () 577 577
Sequence variation in strain: Isolate Shanghai QXC1 () 605 605
Sequence variation in strain: Isolate SZ3 () 607 607
Sequence variation in strain: Isolate Shanghai QXC1 () 608 608
Sequence variation in strain: Isolate GD03 () 609 609
Sequence variation in strain: Isolate GD03 () 613 613
Sequence variation in strain: Isolate GD03 and Isolate SZ3 () 665 665
Sequence variation in strain: Isolate SZ3 () 701 701
Sequence variation in strain: Isolate SZ3 () 743 743
Sequence variation in strain: Isolate GD03 () 743 743
Sequence variation in strain: Isolate SZ3 () 754 754
Sequence variation in strain: Isolate GD03 () 765 765
Sequence variation in strain: Isolate GD01, Isolate GZ50, Isolate GD03 and Isolate () 778 778
Sequence variation in strain: Isolate GD01 () 794 794
Sequence variation in strain: Isolate Shanghai LY () 804 804
Sequence variation in strain: Isolate BJ03 () 860 861
Sequence variation in strain: Isolate SZ3 () 894 894
Sequence variation in strain: Isolate Shanghai LY () 999 999
Sequence variation in strain: Isolate BJ04 () 1001 1001
Sequence variation in strain: Isolate Shanghai QXC1 () 1132 1132
Sequence variation in strain: Isolate Frankfurt 1 and Isolate FRA () 1148 1148
Sequence variation in strain: Isolate GD03 and Isolate SZ3 () 1163 1163
mutagenesis site No effect on human ACE2 binding in vitro. 323 323
mutagenesis site Complete loss of human ACE2 binding in vitro. 348 348
mutagenesis site 90% loss of human ACE2 binding in vitro. 452 452
mutagenesis site Complete loss of human ACE2 binding in vitro. 454 454
mutagenesis site Partial loss of human ACE2 binding in vitro. 463 463
mutagenesis site Complete loss of human ACE2 binding in vitro. 467 467
mutagenesis site Complete loss of human ACE2 binding in vitro. 474 474
mutagenesis site No effect on human ACE2 binding in vitro. 480 480
mutagenesis site 40% loss of cell-cell fusion. 667 667
mutagenesis site No effect on cell-cell fusion. 672 672
mutagenesis site Complete loss of trypsin-induced membrane fusion. 797 797
mutagenesis site Decrease in Golgi localization, and complete loss of COPI bindin 1251 1251
mutagenesis site Decrease in Golgi localization, and complete loss of COPI bindin 1253 1253
strand strand 31 34
strand strand 37 41
strand strand 44 48
strand strand 50 59
strand strand 65 72
strand strand 73 75
strand strand 87 95
strand strand 100 111
strand strand 113 118
strand strand 123 141
turn turn 142 144
strand strand 146 164
strand strand 177 190
strand strand 193 208
strand strand 216 222
strand strand 229 239
strand strand 250 256
strand strand 258 266
strand strand 268 270
strand strand 272 277
turn turn 282 288
strand strand 297 299
strand strand 310 312
helix helix 326 329
helix helix 337 339
strand strand 341 345
strand strand 347 349
helix helix 352 354
strand strand 362 368
helix helix 371 378
strand strand 380 390
helix helix 391 396
strand strand 397 400
helix helix 404 408
strand strand 414 416
strand strand 418 424
helix helix 426 429
strand strand 431 433
strand strand 439 441
strand strand 462 464
strand strand 469 471
strand strand 478 480
strand strand 483 487
helix helix 489 491
strand strand 492 501
strand strand 509 511
strand strand 523 527
strand strand 536 540
strand strand 551 563
turn turn 565 567
strand strand 570 574
strand strand 583 585
turn turn 588 590
strand strand 596 599
helix helix 604 610
turn turn 611 613
strand strand 615 617
strand strand 628 631
strand strand 635 638
strand strand 640 646
strand strand 649 653
strand strand 656 659
strand strand 675 678
strand strand 682 685
strand strand 691 698
strand strand 704 710
strand strand 716 718
helix helix 720 725
helix helix 730 735
helix helix 736 738
strand strand 740 744
helix helix 745 764
strand strand 768 771
helix helix 773 777
strand strand 778 781
turn turn 785 787
strand strand 790 792
strand strand 794 797
helix helix 799 806
helix helix 813 817
strand strand 820 823
strand strand 832 834
strand strand 837 842
helix helix 849 865
helix helix 869 872
helix helix 880 891
strand strand 898 900
helix helix 915 948
helix helix 959 963
turn turn 964 969
helix helix 971 1013
turn turn 1014 1016
strand strand 1027 1032
strand strand 1035 1038
strand strand 1041 1048
strand strand 1054 1059
strand strand 1061 1063
strand strand 1066 1068
strand strand 1070 1074
strand strand 1078 1080
strand strand 1083 1086
strand strand 1089 1091
strand strand 1101 1111
strand strand 1114 1116
helix helix 1148 1151
helix helix 1162 1172
helix helix 1173 1178
helix helix 1182 1192
signal peptide signal peptide 1 13
chain Spike glycoprotein (PRO_0000037208) 14 1255
chain Spike protein S1 (PRO_0000037209) 14 667
chain Spike protein S2 (PRO_0000037210) 668 1255
chain Spike protein S2' (PRO_0000444082) 798 1255
topological domain Extracellular 14 1195
transmembrane region Helical 1196 1216
topological domain Cytoplasmic 1217 1255
Other domain of interest BetaCoV S1-NTD 14 290
Other domain of interest BetaCoV S1-CTD 321 513
region of interest Receptor-binding domain 306 527
region of interest Receptor-binding motif; binding to human ACE2 424 494
region of interest Fusion peptide 1 798 819
region of interest Fusion peptide 2 817 837
region of interest Heptad repeat 1 902 952
region of interest Heptad repeat 2 1145 1184
coiled-coil region coiled-coil region 931 975
coiled-coil region coiled-coil region 1157 1185
short sequence motif KxHxx 1251 1255
compositionally biased region Cys-rich 1217 1236
Other site of interest Cleavage 667 668
Other site of interest Cleavage 797 798
glycosylation site N-linked (GlcNAc...) asparagine; by host () 29 29
glycosylation site N-linked (GlcNAc...) asparagine; by host () 65 65
glycosylation site N-linked (GlcNAc...) asparagine; by host () 73 73
glycosylation site N-linked (GlcNAc...) asparagine; by host () 109 109
glycosylation site N-linked (GlcNAc...) asparagine; by host () 118 118
glycosylation site N-linked (GlcNAc...) asparagine; by host () 119 119
glycosylation site N-linked (GlcNAc...) asparagine; by host () 158 158
glycosylation site N-linked (GlcNAc...) asparagine; by host () 227 227
glycosylation site N-linked (GlcNAc...) asparagine; by host () 269 269
glycosylation site N-linked (GlcNAc...) asparagine; by host () 318 318
glycosylation site N-linked (GlcNAc...) asparagine; by host () 330 330
glycosylation site N-linked (GlcNAc...) asparagine; by host () 357 357
glycosylation site N-linked (GlcNAc...) asparagine; by host () 589 589
glycosylation site N-linked (GlcNAc...) asparagine; by host () 602 602
glycosylation site N-linked (GlcNAc...) asparagine; by host () 691 691
glycosylation site N-linked (GlcNAc...) asparagine; by host () 699 699
glycosylation site N-linked (GlcNAc...) asparagine; by host () 783 783
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1056 1056
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1080 1080
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1116 1116
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1140 1140
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1155 1155
glycosylation site N-linked (GlcNAc...) asparagine; by host () 1176 1176
disulfide bond disulfide bond 19 133
disulfide bond disulfide bond 128 159
disulfide bond disulfide bond 278 288
disulfide bond disulfide bond 323 348
disulfide bond disulfide bond 366 419
disulfide bond disulfide bond 378 511
disulfide bond disulfide bond 467 474
disulfide bond disulfide bond 822 833
Sequence variation in strain: Isolate GZ50 () 49 49
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate GZ5 () 77 77
Sequence variation in strain: Isolate GD03 () 78 78
Sequence variation in strain: Isolate Shanghai LY () 118 118
Sequence variation in strain: Isolate GD03 () 139 139
Sequence variation in strain: Isolate BJ03 () 144 144
Sequence variation in strain: Isolate GD03 () 147 147
Sequence variation in strain: Isolate Shanghai LY () 193 193
Sequence variation in strain: Isolate SZ3 () 227 227
Sequence variation in strain: Isolate GD01 and Isolate SZ3 () 239 239
Sequence variation in strain: Isolate BJ01, Isolate BJ02, Isolate BJ03, Isolate BJ0 () 244 244
Sequence variation in strain: Isolate SZ3 () 261 261
Sequence variation in strain: Isolate GD01 and Isolate BJ02 () 311 311
Sequence variation in strain: Isolate GD01, Isolate GD03 and Isolate SZ3; no effect () 344 344
Sequence variation in strain: Isolate GD03 and Isolate SZ3; no effect on affinity w () 360 360
Sequence variation in strain: Isolate Shanghai LY () 426 426
Sequence variation in strain: Isolate Shanghai LY () 437 437
Sequence variation in strain: Isolate GD03 () 472 472
Sequence variation in strain: Isolate SZ3; 20fold decrease of affinity with human A () 479 479
Sequence variation in strain: Isolate GD03 () 480 480
Sequence variation in strain: Isolate GD03 and Isolate SZ3; 20fold decrease of affi () 487 487
Sequence variation in strain: Isolate GD01 () 501 501
Sequence variation in strain: Isolate Tor2 and Isolate Shanghai QXC1 () 577 577
Sequence variation in strain: Isolate Shanghai QXC1 () 605 605
Sequence variation in strain: Isolate SZ3 () 607 607
Sequence variation in strain: Isolate Shanghai QXC1 () 608 608
Sequence variation in strain: Isolate GD03 () 609 609
Sequence variation in strain: Isolate GD03 () 613 613
Sequence variation in strain: Isolate GD03 and Isolate SZ3 () 665 665
Sequence variation in strain: Isolate SZ3 () 701 701
Sequence variation in strain: Isolate SZ3 () 743 743
Sequence variation in strain: Isolate GD03 () 743 743
Sequence variation in strain: Isolate SZ3 () 754 754
strand strand 1078 1080
Sequence variation in strain: Isolate GD03 () 765 765
Sequence variation in strain: Isolate GD01, Isolate GZ50, Isolate GD03 and Isolate () 778 778
Sequence variation in strain: Isolate GD01 () 794 794
Sequence variation in strain: Isolate Shanghai LY () 804 804
Sequence variation in strain: Isolate BJ03 () 860 861
Sequence variation in strain: Isolate SZ3 () 894 894
Sequence variation in strain: Isolate Shanghai LY () 999 999
Sequence variation in strain: Isolate BJ04 () 1001 1001
Sequence variation in strain: Isolate Shanghai QXC1 () 1132 1132
Sequence variation in strain: Isolate Frankfurt 1 and Isolate FRA () 1148 1148
Sequence variation in strain: Isolate GD03 and Isolate SZ3 () 1163 1163
mutagenesis site No effect on human ACE2 binding in vitro. 323 323
mutagenesis site Complete loss of human ACE2 binding in vitro. 348 348
mutagenesis site 90% loss of human ACE2 binding in vitro. 452 452
mutagenesis site Complete loss of human ACE2 binding in vitro. 454 454
mutagenesis site Partial loss of human ACE2 binding in vitro. 463 463
mutagenesis site Complete loss of human ACE2 binding in vitro. 467 467
mutagenesis site Complete loss of human ACE2 binding in vitro. 474 474
mutagenesis site No effect on human ACE2 binding in vitro. 480 480
mutagenesis site 40% loss of cell-cell fusion. 667 667
mutagenesis site No effect on cell-cell fusion. 672 672
mutagenesis site Complete loss of trypsin-induced membrane fusion. 797 797
mutagenesis site Decrease in Golgi localization, and complete loss of COPI bindin 1251 1251
mutagenesis site Decrease in Golgi localization, and complete loss of COPI bindin 1253 1253
strand strand 31 34
strand strand 37 41
strand strand 44 48
strand strand 50 59
strand strand 65 72
strand strand 73 75
strand strand 87 95
strand strand 100 111
strand strand 113 118
strand strand 123 141
turn turn 142 144
strand strand 146 164
strand strand 177 190
strand strand 193 208
strand strand 216 222
strand strand 229 239
strand strand 250 256
strand strand 258 266
strand strand 268 270
strand strand 272 277
turn turn 282 288
strand strand 297 299
strand strand 310 312
helix helix 326 329
helix helix 337 339
strand strand 341 345
strand strand 347 349
helix helix 352 354
strand strand 362 368
helix helix 371 378
strand strand 380 390
helix helix 391 396
strand strand 397 400
helix helix 404 408
strand strand 414 416
strand strand 418 424
helix helix 426 429
strand strand 431 433
strand strand 439 441
strand strand 462 464
strand strand 471 473
strand strand 478 480
strand strand 483 487
helix helix 489 491
strand strand 492 501
strand strand 509 511
strand strand 523 527
strand strand 536 540
strand strand 551 563
turn turn 565 567
strand strand 570 574
strand strand 583 585
turn turn 588 590
strand strand 596 599
helix helix 604 610
turn turn 611 613
strand strand 615 617
strand strand 628 631
strand strand 635 638
strand strand 640 646
strand strand 649 653
strand strand 656 659
strand strand 675 678
strand strand 682 685
strand strand 691 698
strand strand 704 710
strand strand 716 718
helix helix 720 725
helix helix 730 735
helix helix 736 738
strand strand 740 744
helix helix 745 764
strand strand 768 771
helix helix 773 777
strand strand 778 781
turn turn 785 787
strand strand 790 792
strand strand 794 797
helix helix 799 806
helix helix 813 817
strand strand 820 823
strand strand 832 834
strand strand 837 842
helix helix 849 865
helix helix 869 872
helix helix 880 891
strand strand 898 900
helix helix 915 948
helix helix 959 963
turn turn 964 969
helix helix 971 1013
turn turn 1014 1016
strand strand 1027 1032
strand strand 1035 1038
strand strand 1041 1048
strand strand 1054 1059
strand strand 1061 1063
strand strand 1066 1068
strand strand 1070 1074
strand strand 1083 1086
strand strand 1089 1091
strand strand 1101 1111
strand strand 1114 1116
helix helix 1148 1151
helix helix 1162 1172
helix helix 1173 1178
helix helix 1182 1192

Secuencia AA

Contexto Génico

Variantes

PosRefAltPaísesInfo.
5 L F Argentina:2 Mapeado en 0 estructuras.
18 L F Argentina:1 Mapeado en 0 estructuras.
20 T I Argentina:2 Mapeado en 0 estructuras.
21 R I Argentina:1 Mapeado en 0 estructuras.
24 L S Argentina:1 Mapeado en 0 estructuras.
40 D E Argentina:1 Mapeado en 0 estructuras.
49 H Y Argentina:3 Mapeado en 0 estructuras.
64 W L Argentina:1 Mapeado en 0 estructuras.
67 A V Argentina:1 Mapeado en 0 estructuras.
70 V F Argentina:1 Mapeado en 0 estructuras.
96 E D Argentina:1 Mapeado en 0 estructuras.
138 D H Argentina:2 Mapeado en 0 estructuras.
176 L F Argentina:1 Mapeado en 0 estructuras.
181 G V Argentina:1 Mapeado en 0 estructuras.
182 K R Argentina:1 Mapeado en 0 estructuras.
183 Q * Argentina:1 Mapeado en 0 estructuras.
284 T I Argentina:1 Mapeado en 0 estructuras.
322 P L Argentina:1 Mapeado en 0 estructuras.
414 Q R Argentina:11 Mapeado en 0 estructuras.
432 C * Argentina:1 Mapeado en 0 estructuras.
433 V N Argentina:1 Mapeado en 0 estructuras.
435 A V Argentina:1 Mapeado en 0 estructuras.
441 L F Argentina:4 Mapeado en 0 estructuras.
442 D E Argentina:1 Mapeado en 0 estructuras.
442 D N Argentina:1 Mapeado en 0 estructuras.
443 S I Argentina:1 Mapeado en 0 estructuras.
443 S L Argentina:1 Mapeado en 0 estructuras.
443 S N Argentina:1 Mapeado en 0 estructuras.
444 K D Argentina:1 Mapeado en 0 estructuras.
444 K R Argentina:1 Mapeado en 0 estructuras.
445 V G Argentina:1 Mapeado en 0 estructuras.
446 G Y Argentina:1 Mapeado en 0 estructuras.
447 G L Argentina:1 Mapeado en 0 estructuras.
448 N Y Argentina:1 Mapeado en 0 estructuras.
452 L M Argentina:1 Mapeado en 0 estructuras.
452 L Q Argentina:82 Mapeado en 0 estructuras.
452 L R Argentina:8 Mapeado en 0 estructuras.
463 P L Argentina:1 Mapeado en 0 estructuras.
470 T A Argentina:1 Mapeado en 0 estructuras.
470 T N Argentina:1 Mapeado en 0 estructuras.
477 S I Argentina:1 Mapeado en 0 estructuras.
478 T K Argentina:3 Mapeado en 0 estructuras.
484 E K Argentina:65 Mapeado en 0 estructuras.
490 F S Argentina:82 Mapeado en 0 estructuras.
501 N Y Argentina:73 Mapeado en 0 estructuras.
522 A P Argentina:1 Mapeado en 0 estructuras.
522 A S Argentina:1 Mapeado en 0 estructuras.
551 V F Argentina:1 Mapeado en 0 estructuras.
567 R K Argentina:1 Mapeado en 0 estructuras.
570 A D Argentina:40 Mapeado en 0 estructuras.
572 T I Argentina:5 Mapeado en 0 estructuras.
574 D Y Argentina:2 Mapeado en 0 estructuras.
583 E D Argentina:1 Mapeado en 0 estructuras.
584 I V Argentina:1 Mapeado en 0 estructuras.
614 D G Argentina:1029 Mapeado en 0 estructuras.
620 V L Argentina:1 Mapeado en 0 estructuras.
621 P L Argentina:1 Mapeado en 0 estructuras.
622 V I Argentina:2 Mapeado en 0 estructuras.
626 A S Argentina:26 Mapeado en 0 estructuras.
626 A V Argentina:1 Mapeado en 0 estructuras.
647 A S Argentina:1 Mapeado en 0 estructuras.
654 E Q Argentina:35 Mapeado en 0 estructuras.
655 H Y Argentina:33 Mapeado en 0 estructuras.
658 N D Argentina:4 Mapeado en 0 estructuras.
675 Q H Argentina:4 Mapeado en 0 estructuras.
677 Q H Argentina:2 Mapeado en 0 estructuras.
681 P H Argentina:45 Mapeado en 0 estructuras.
688 A S Argentina:1 Mapeado en 0 estructuras.
688 A V Argentina:3 Mapeado en 0 estructuras.
689 S I Argentina:1 Mapeado en 0 estructuras.
697 M I Argentina:1 Mapeado en 0 estructuras.
701 A V Argentina:7 Mapeado en 0 estructuras.
702 E Q Argentina:1 Mapeado en 0 estructuras.
704 S L Argentina:2 Mapeado en 0 estructuras.
714 I V Argentina:1 Mapeado en 0 estructuras.
716 T I Argentina:40 Mapeado en 0 estructuras.
719 T I Argentina:2 Mapeado en 0 estructuras.
731 M I Argentina:1 Mapeado en 0 estructuras.
732 T A Argentina:4 Mapeado en 0 estructuras.
745 D A Argentina:1 Mapeado en 0 estructuras.
745 D G Argentina:1 Mapeado en 0 estructuras.
745 D S Argentina:2 Mapeado en 0 estructuras.
746 S * Argentina:1 Mapeado en 0 estructuras.
746 S L Argentina:1 Mapeado en 0 estructuras.
759 F L Argentina:1 Mapeado en 0 estructuras.
778 T I Argentina:1 Mapeado en 0 estructuras.
812 P L Argentina:6 Mapeado en 0 estructuras.
821 L I Argentina:1 Mapeado en 0 estructuras.
987 V D Argentina:1 Mapeado en 0 estructuras.
1076 T I Argentina:1 Mapeado en 0 estructuras.
1084 D Y Argentina:1 Mapeado en 0 estructuras.
1099 G D Argentina:1 Mapeado en 0 estructuras.
1101 H D Argentina:1 Mapeado en 0 estructuras.
1117 T I Argentina:2 Mapeado en 0 estructuras.
1124 G V Argentina:1 Mapeado en 0 estructuras.
1162 P L Argentina:1 Mapeado en 0 estructuras.
1176 V A Argentina:2 Mapeado en 0 estructuras.
1176 V F Argentina:3 Mapeado en 0 estructuras.
1199 D N Argentina:1 Mapeado en 0 estructuras.
1243 C F Argentina:1 Mapeado en 0 estructuras.
1265 L R Argentina:1 Mapeado en 0 estructuras.
1266 K V Argentina:1 Mapeado en 0 estructuras.
1267 G K Argentina:1 Mapeado en 0 estructuras.
1268 V L Argentina:1 Mapeado en 0 estructuras.
1269 K H Argentina:1 Mapeado en 0 estructuras.
1270 L Y Argentina:1 Mapeado en 0 estructuras.
1271 H T Argentina:1 Mapeado en 0 estructuras.
1272 Y * Argentina:1 Mapeado en 0 estructuras.
1274 * N Argentina:1 Mapeado en 0 estructuras.