NS7a

ORF7a protein

Función

Biological Process

Localización Celular

Keywords Uniprot

DBIdentificador
Proteomes UP000131569
EMBL AY323977
KEGG vg:1489674
Proteomes UP000138690
EMBL AY278741
UnipAcc Q7TA11
EMBL AY463059
EMBL AY427439
EMBL AY278491
EMBL AP006561
EMBL AY278490
SMR P59635
EMBL AY322208
EMBL AY274119
Proteomes UP000137377
PRIDE P59635
Proteomes UP000145651
EMBL AP006559
Proteomes UP000121636
UnipAcc P59635
EMBL AY291315
BioGRID 4383920
EMBL AY278554
EMBL AY278488
Proteomes UP000146181
Proteomes UP000146108
Proteomes UP000172416
EvolutionaryTrace P59635
EMBL AP006560
UnipAcc Q7TA17
EMBL AY278487
Proteomes UP000103670
EMBL AP006557
Pfam PF08779
Proteomes UP000131955
RefSeq NP_828857.1
Proteomes UP000164441
SIGNOR P59635
Proteomes UP000148194
EMBL AY291451
EMBL AY282752
InterPro IPR014888
Proteomes UP000146296
EMBL AY278489
PROSITE PS51919
Proteomes UP000109640
EMBL AP006558
Proteomes UP000000354
ELM P59635
UnipAcc NS7A_SARS
InterPro IPR036495
EMBL AY338174
Gene3D 2.60.40.1550
Proteomes UP000153467
Proteomes UP000143093
SUPFAM SSF117066
EMBL AY310120
EMBL AY279354
Proteomes UP000116947
EMBL AY338175
IntAct P59635
Proteomes UP000160648
EMBL AY348314
GeneID 1489674

Estructura/s

TipoCodNombreDrogabilidad
PDB 1xak VIRAL PROTEIN 0.92
PDB 1yo4 VIRAL PROTEIN 0.668

Anotación

Tipo Identificador InicioFin
signal peptide signal peptide 1 15
chain ORF7a protein (PRO_0000037435) 16 122
topological domain Virion surface 16 96
transmembrane region Helical 97 117
topological domain Intravirion 118 122
Other domain of interest X4e 16 81
short sequence motif Di-lysine motif 118 122
disulfide bond disulfide bond 23 58
disulfide bond disulfide bond 35 67
Sequence variation in strain: Isolate Shanghai LY () 38 38
mutagenesis site Complete loss of signal sequence cleavage. 14 18
mutagenesis site Induces rapid exit from the endoplasmic reticulum. 118 120
strand strand 16 24
strand strand 27 32
strand strand 34 37
strand strand 39 44
turn turn 50 52
strand strand 53 57
strand strand 60 66
strand strand 72 80
strand strand 82 84
strand strand 89 93
strand strand 95 97
signal peptide signal peptide 1 15
chain ORF7a protein (PRO_0000037435) 16 122
topological domain Virion surface 16 96
transmembrane region Helical 97 117
topological domain Intravirion 118 122
Other domain of interest X4e 16 81
short sequence motif Di-lysine motif 118 122
disulfide bond disulfide bond 23 58
disulfide bond disulfide bond 35 67
Sequence variation in strain: Isolate Shanghai LY () 38 38
mutagenesis site Complete loss of signal sequence cleavage. 14 18
mutagenesis site Induces rapid exit from the endoplasmic reticulum. 118 120
strand strand 16 24
strand strand 27 32
strand strand 34 37
strand strand 39 44
turn turn 50 52
strand strand 53 57
strand strand 60 66
strand strand 72 80
strand strand 82 84
strand strand 89 93
strand strand 95 97

Secuencia AA

Contexto Génico

Variantes

PosRefAltPaísesInfo.
25 R I Argentina:6 Mapeado en 0 estructuras.
44 S L Argentina:1 Mapeado en 0 estructuras.
46 F L Argentina:1 Mapeado en 0 estructuras.
99 P S Argentina:1 Mapeado en 0 estructuras.