N

['Protein N', 'NC']
Nucleoprotein

Función

Biological Process

Molecular Function/s

Localización Celular

Keywords Uniprot

DBIdentificador
Proteomes UP000131569
EMBL AY323977
Proteomes UP000138690
EMBL AY283794
GeneID 1489678
EMBL AY278741
InterPro IPR037195
EMBL AY427439
EMBL AY278491
iPTMnet P59595
EMBL AP006561
EMBL AY307165
MINT P59595
EMBL AY278490
EMBL AY322208
EMBL AY274119
Proteomes UP000137377
SUPFAM SSF110304
EMBL AY304492
Proteomes UP000145651
EMBL AP006559
UnipAcc NCAP_SARS
Proteomes UP000121636
UnipGene N
SIGNOR P59595
InterPro IPR037179
EvolutionaryTrace P59595
UnipName Protein N
EMBL AY291315
EMBL AY362698
EMBL AY278554
UnipAcc Q80E50
EMBL AY278488
Proteomes UP000146181
Proteomes UP000146108
Proteomes UP000172416
SMR P59595
EMBL AP006560
EMBL AY278487
Proteomes UP000103670
ABCD P59595
EMBL AP006557
EMBL AY283797
Proteomes UP000131955
EMBL AY304495
UnipAcc Q7T3Z4
Proteomes UP000148194
InterPro IPR043505
UnipName NC
EMBL AY291451
InterPro IPR001218
EMBL AY362699
EMBL AY282752
Pfam PF00937
RefSeq NP_828858.1
Proteomes UP000146296
EMBL AY278489
IntAct P59595
PIRSF PIRSF003888
KEGG vg:1489678
EMBL AY290752
BioGRID 4383916
Proteomes UP000109640
DisProt DP00948
EMBL AP006558
Proteomes UP000000354
KO K24106
EMBL AY283795
HAMAP MF_04096
EMBL AY321118
EMBL AY338174
ComplexPortal CPX-5720
UnipAcc Q7TF99
Proteomes UP000153467
Proteomes UP000143093
UnipAcc P59595
UnipAcc Q7TA14
EMBL AY310120
EMBL AY279354
Proteomes UP000116947
SUPFAM SSF103068
EMBL AY338175
EMBL AY283796
PRIDE P59595
Proteomes UP000160648
EMBL AY348314
PROSITE PS51929
PROSITE PS51928

Estructura/s

TipoCodNombreDrogabilidad
PDB 2cjr VIRAL PROTEIN 0.458
PDB 2gib VIRAL PROTEIN 0.485
PDB 2jw8 VIRAL PROTEIN 0.79
PDB 6iex IMMUNE SYSTEM 0.72
PDB 2ofz VIRAL PROTEIN 0.526
PDB 1ssk STRUCTURAL PROTEIN 0.736
PDB 1x7q IMMUNE SYSTEM 0.51
PDB 2og3 VIRAL PROTEIN 0.648
PDB 3i6l IMMUNE SYSTEM 0.791

Anotación

Tipo Identificador InicioFin
chain Nucleoprotein (PRO_0000106003) 1 422
region of interest RNA-binding 42 187
region of interest RNA-binding 45 181
region of interest Dimerization 259 362
compositionally biased region Ser-rich 181 213
compositionally biased region Poly-Leu 220 225
compositionally biased region Poly-Gln 240 245
compositionally biased region Poly-Lys 370 376
Post-translationally modified residue Phosphoserine; by host 177 177
Sequence variation in strain: Isolate Frankfurt 1 and Isolate FRA () 50 50
Sequence variation in strain: Isolate BJ03 () 154 154
Sequence variation in strain: Isolate CUHK-Su10 () 193 193
Sequence variation in strain: Isolate Shanghai LY () 325 326
strand strand 56 59
strand strand 61 63
strand strand 77 79
helix helix 81 83
strand strand 85 91
strand strand 94 96
turn turn 98 100
strand strand 102 104
strand strand 108 113
turn turn 118 121
strand strand 131 135
strand strand 140 142
turn turn 145 147
turn turn 152 154
strand strand 254 258
helix helix 260 262
helix helix 271 275
turn turn 282 284
helix helix 290 295
helix helix 296 298
helix helix 302 306
helix helix 312 318
strand strand 319 325
strand strand 330 340
helix helix 347 357
helix helix 360 363
chain Nucleoprotein (PRO_0000106003) 1 422
Other domain of interest CoV N NTD 49 176
Other domain of interest CoV N CTD 248 365
region of interest RNA-binding 42 187
region of interest RNA-binding 45 181
region of interest Dimerization 259 362
compositionally biased region Ser-rich 181 213
compositionally biased region Poly-Leu 220 225
compositionally biased region Poly-Gln 240 245
compositionally biased region Poly-Lys 370 376
Post-translationally modified residue Phosphoserine; by host 177 177
Sequence variation in strain: Isolate Frankfurt 1 and Isolate FRA () 50 50
Sequence variation in strain: Isolate BJ03 () 154 154
Sequence variation in strain: Isolate CUHK-Su10 () 193 193
Sequence variation in strain: Isolate Shanghai LY () 325 326
strand strand 56 59
strand strand 61 63
strand strand 77 79
helix helix 81 83
strand strand 85 91
strand strand 94 96
turn turn 98 100
strand strand 102 104
strand strand 108 113
turn turn 118 121
strand strand 131 135
strand strand 140 142
turn turn 145 147
turn turn 152 154
strand strand 254 258
helix helix 260 262
helix helix 271 275
turn turn 282 284
helix helix 290 295
helix helix 296 298
helix helix 302 306
helix helix 312 318
strand strand 319 325
strand strand 330 340
helix helix 347 357
helix helix 360 363

Secuencia AA

Contexto Génico

Variantes

PosRefAltPaísesInfo.
37 S L Argentina:1 Mapeado en 0 estructuras.
46 P S Argentina:1 Mapeado en 0 estructuras.
103 D Y Argentina:2 Mapeado en 0 estructuras.
134 A V Argentina:1 Mapeado en 0 estructuras.
180 S I Argentina:1 Mapeado en 0 estructuras.
196 N I Argentina:1 Mapeado en 0 estructuras.
197 S L Argentina:167 Mapeado en 0 estructuras.
199 P S Argentina:1 Mapeado en 0 estructuras.
203 R K Argentina:119 Mapeado en 0 estructuras.
204 G R Argentina:119 Mapeado en 0 estructuras.
282 T I Argentina:1 Mapeado en 0 estructuras.
292 I T Argentina:61 Mapeado en 0 estructuras.
319 R H Argentina:1 Mapeado en 0 estructuras.
325 T I Argentina:4 Mapeado en 0 estructuras.
364 P L Argentina:1 Mapeado en 0 estructuras.
379 T I Argentina:3 Mapeado en 0 estructuras.
393 T I Argentina:3 Mapeado en 0 estructuras.
410 S F Argentina:4 Mapeado en 0 estructuras.
416 S L Argentina:2 Mapeado en 0 estructuras.
418 Q * Argentina:1 Mapeado en 0 estructuras.